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评估牙科外科医生对双膦酸盐的理解:对口腔外科患者健康的影响。

Assessing dental surgeons' understanding of bisphosphonates: Implications for patient health in oral surgery.

作者信息

Rocha Cortez Teles de Alencar Vilson, Ribeiro Paulino Marcília, Andrea Luna Martinis de Alencar Inês, Ribeiro-Filho Jaime, Valéria de Oliveira Braz Ana, Fagner Ferreira Matias Edinardo, Paulo Martins de Lima João, Giesta Lemos Florencio Sloana, Douglas Melo Coutinho Henrique, Marcos Montagner Antônio

机构信息

Dr. Leão Sampaio University Center - UNILEÃO, Juazeiro do Norte, Ceará, Brazil.

Solutions Estética Oral e Facial, Crato, Ceará, Brazil.

出版信息

Saudi Dent J. 2024 Jan;36(1):180-186. doi: 10.1016/j.sdentj.2023.09.011. Epub 2023 Sep 29.

DOI:10.1016/j.sdentj.2023.09.011
PMID:38375400
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10874787/
Abstract

OBJECTIVES

This study aimed to analyze the knowledge of dental surgeons concerning the pharmacological effects of bisphosphonates (BP) and their impact on the health of patients undergoing oral surgery treatment.

MATERIALS AND METHODS

A quantitative study was conducted with professionals in the Cariri region of Ceará, Brazil. The data were collected using a semi-structured questionnaire to interview the dental surgeons who met the inclusion criteria. The data were analyzed by Chi-square and Fischer's Exact tests using the SPSS program version 22.0.

RESULTS

The results indicated that most interviewed subjects have no experience with the dental treatment of individuals under treatment with bisphosphonates. When a sample of the medication was presented, a significant number of the participants (65.3%) did not recognize the drug. Among those who recognized it, 66.5% did not know how to treat bisphosphonate-using patients in the clinical routine. However, 95.1% of the professionals who recognized the need to discontinue these drugs admitted contacting the prescriber to establish the best dental conduct. Our results also showed that recently graduated professionals better understood the need to stop BP use before invasive treatment, although they did not know the protocol.

CONCLUSION

In conclusion, a better knowledge of the pharmacological effects of BP is crucial for conducting adequate anamnesis, requesting additional tests, and performing medical monitoring, which has a significant impact on the clinical practice of dental surgeons.

摘要

目的

本研究旨在分析牙科医生对双膦酸盐(BP)药理作用的了解及其对接受口腔外科治疗患者健康的影响。

材料与方法

对巴西塞阿拉州卡里里地区的专业人员进行了一项定量研究。使用半结构化问卷收集数据,以采访符合纳入标准的牙科医生。使用SPSS 22.0版程序通过卡方检验和费舍尔精确检验对数据进行分析。

结果

结果表明,大多数接受采访的受试者没有治疗正在使用双膦酸盐的个体的牙科治疗经验。当展示一种药物样本时,相当数量的参与者(65.3%)不认识该药物。在认识该药物的人中,66.5%不知道在临床常规中如何治疗使用双膦酸盐的患者。然而,95.1%认识到需要停用这些药物的专业人员承认会联系开处方者以确定最佳牙科治疗方案。我们的结果还表明,尽管刚毕业的专业人员不了解治疗方案,但他们更清楚在侵入性治疗前停用BP的必要性。

结论

总之,更好地了解BP的药理作用对于进行充分的问诊、要求进行额外检查以及进行医学监测至关重要,这对牙科医生的临床实践有重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/b7e8920f8f66/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/d73a4e23d04f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/d0f0a3860fcb/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/1147c58f0526/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/b7e8920f8f66/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/d73a4e23d04f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/d0f0a3860fcb/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/1147c58f0526/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1481/10874787/b7e8920f8f66/gr4.jpg

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BMC Oral Health. 2022 Jul 17;22(1):291. doi: 10.1186/s12903-022-02330-y.
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Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration.血小板浓缩物在口腔和颅面再生中的再生作用。
Front Cardiovasc Med. 2019 Sep 3;6:126. doi: 10.3389/fcvm.2019.00126. eCollection 2019.
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Systematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw.
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Novel insight into the management of bisphosphonate-related osteonecrosis of the jaw (BRONJ).对双膦酸盐相关颌骨坏死(BRONJ)管理的新见解。
Jpn Dent Sci Rev. 2019 Nov;55(1):95-102. doi: 10.1016/j.jdsr.2018.09.002. Epub 2019 May 17.
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Association between biomarkers and medication-related osteonecrosis of the jaws: a systematic review.生物标志物与药物相关性颌骨坏死的关联:系统评价。
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Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment.药物相关性颌骨坏死:预防、诊断和治疗的定义及最佳实践。
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