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分娩第二产程延长后经干预与期待管理对盆底功能障碍的影响:基于人群的问卷调查和队列研究。

Pelvic floor dysfunction after intervention, compared with expectant management, in prolonged second stage of labour: A population-based questionnaire and cohort study.

机构信息

Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

BB Sankt Göran, Capio Sankt Göran Hospital, Stockholm, Sweden.

出版信息

BJOG. 2024 Aug;131(9):1279-1289. doi: 10.1111/1471-0528.17792. Epub 2024 Feb 20.

DOI:10.1111/1471-0528.17792
PMID:38375535
Abstract

OBJECTIVE

To investigate the effect of vacuum extraction (VE) or caesarean section (CS), compared with expectant management, on pelvic floor dysfunction (PFD) 1-2 years postpartum in primiparous women with a prolonged second stage of labour.

DESIGN

A population-based questionnaire and cohort study.

SETTING

Stockholm, Sweden.

POPULATION

A cohort of 1302 primiparous women with a second stage duration of ≥3 h, delivering from December 2017 to November 2018.

METHODS

The 1-year follow-up questionnaire from the Swedish National Perineal Laceration Register was distributed 12-24 months postpartum. Exposure was VE or CS at 3-4 h or 4-5 h, compared with expectant management.

MAIN OUTCOME MEASURES

Pelvic floor dysfunction was defined as at least weekly symptoms of urinary incontinence, pelvic organ prolapse or a Wexner score of ≥4. The risk of PFD was calculated using Poisson regression with robust variance estimation, presented as crude and adjusted relative risks (RRs and aRRs) with 95% confidence intervals (95% CIs). The implication of obstetric anal sphincter injury (OASI) on pelvic floor disorders was investigated through mediation analysis.

RESULTS

In total, 35.1% of women reported PFD. Compared with expectant management, the risk of PFD was increased after VE at 3-4 h (aRR 1.33, 95% CI 1.06-1.65) and 4-5 h (aRR 1.34, 95% CI 1.05-1.70), but remained unchanged after CS. The increased risk after VE was not mediated by OASI.

CONCLUSIONS

Pelvic floor dysfunction was common in primiparous women after a prolonged second stage, and the risk of PFD increased after VE but was unaffected by CS, compared with expectant management. If a spontaneous vaginal delivery eventually occurred, allowing an extended duration of labour did not increase the risk of PFD.

摘要

目的

探讨与期待管理相比,真空吸引(VE)或剖宫产(CS)对产程第二阶段延长的初产妇产后 1-2 年盆底功能障碍(PFD)的影响。

设计

基于人群的问卷调查和队列研究。

地点

瑞典斯德哥尔摩。

人群

2017 年 12 月至 2018 年 11 月期间分娩的第二产程持续时间≥3 小时的 1302 例初产妇队列。

方法

在产后 12-24 个月时,从瑞典全国会阴裂伤登记处的 1 年随访问卷中发放问卷。暴露于 VE 或 CS 在 3-4 小时或 4-5 小时,与期待管理相比。

主要观察指标

盆底功能障碍定义为每周至少出现一次尿失禁、盆腔器官脱垂或 Wexner 评分≥4 分。使用泊松回归和稳健方差估计计算 PFD 的风险,以粗风险比(RR)和调整后相对风险(RR 和 aRR)和 95%置信区间(95%CI)表示。通过中介分析探讨产科肛门括约肌损伤(OASI)对盆底疾病的影响。

结果

共有 35.1%的女性报告患有 PFD。与期待管理相比,VE 在 3-4 小时(aRR 1.33,95%CI 1.06-1.65)和 4-5 小时(aRR 1.34,95%CI 1.05-1.70)时 PFD 的风险增加,但 CS 后风险不变。VE 后风险增加不是由 OASI 介导的。

结论

在第二产程延长后,初产妇盆底功能障碍很常见,与期待管理相比,VE 后 PFD 的风险增加,但 CS 后不受影响。如果最终自然阴道分娩,延长产程不会增加 PFD 的风险。

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