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低钠饮食并摄入充足水分可提高梅尼埃病的临床疗效。

Low-sodium diet with adequate water intake improved the clinical efficacy in Ménière's disease.

机构信息

Department of Otolaryngology, Foshan Fosun Chancheng Hospital, Foshan City, Guangdong Province, China.

Department of Nursing, Foshan Fosun Chancheng Hospital, Foshan City, Guangdong Province, China.

出版信息

Acta Otolaryngol. 2024 Jan;144(1):14-18. doi: 10.1080/00016489.2024.2315302. Epub 2024 Feb 20.

Abstract

BACKGROUND

Ménière's disease (MD) is a common idiopathic inner ear disorder in otorhinolaryngology characterized by recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus and ear fullness.

OBJECTIVE

To study the effects of low-sodium diet with adequate water intake on the clinical efficacy in MD.

METHODS

Fifty patients diagnosed with stage-3 unilateral MD were randomly divided into control group( = 25) and experimental group( = 25). The control group was given routine medication therapy, and the experimental group was restricted to an sodium intake of 1500 mg/d and a water intake of 35 ml/kg/d based in addition to the routine medication therapy. The two groups were assessed using pure tone audiometry, electrocochleography, Tinnitus Handicap Inventory (THI), and Dizziness Handicap Inventory (DHI).

RESULTS

The pure tone audiometry and electrocochleography showed better improvements after treatment in the experimental group than the control group ( < 0.05). The THI improved values in the experimental group were significantly higher than the control group ( < 0.001). The DHI improved values in the experimental group were significantly higher than the control group ( = 0.004).

CONCLUSIONS AND SIGNIFICANCE

Low-sodium diet with adequate water intake improved the hearing and alleviated vertigo and tinnitus in MD patients.

摘要

背景

梅尼埃病(MD)是耳鼻喉科常见的特发性内耳疾病,其特征为反复发作性眩晕、波动性感音神经性听力损失、耳鸣和耳闷胀感。

目的

研究低钠饮食加充足水分摄入对 MD 患者的临床疗效的影响。

方法

将 50 例单侧 MD Ⅲ期患者随机分为对照组(n=25)和实验组(n=25)。对照组给予常规药物治疗,实验组在常规药物治疗的基础上限制钠摄入量为 1500mg/d,水分摄入量为 35ml/kg/d。采用纯音听阈测试、耳蜗电图、耳鸣残疾量表(THI)和眩晕残疾量表(DHI)评估两组患者。

结果

实验组的纯音听阈测试和耳蜗电图治疗后的改善情况均优于对照组(<0.05)。实验组的 THI 改善值明显高于对照组(<0.001)。实验组的 DHI 改善值明显高于对照组(=0.004)。

结论和意义

低钠饮食加充足水分摄入可改善 MD 患者的听力,并减轻眩晕和耳鸣。

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