Wei Shijie, Lv Hao, Yang Dianhui, Zhang Lili, Li Xuhao, Ning Yike, Tang Yu, Wu Xinyu, Han Jing
School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, China.
Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Front Neurol. 2024 Feb 6;15:1342111. doi: 10.3389/fneur.2024.1342111. eCollection 2024.
Migraine imposes a substantial global burden, impacting patients and society. Pharmacotherapy, as a primary treatment, entails specific adverse reactions. Emphasizing these reactions is pivotal for improving treatment strategies and enhancing patients' well-being. Thus, we conducted a comprehensive bibliometric and visual analysis of relevant literature.
We conducted a comprehensive search on the Science Citation Index Expanded within the Web of Science, restricting the literature for analysis based on criteria such as document type, publication date, and language. Subsequently, we utilized various analytical tools, including VOSviewer, Scimago Graphica, the R package 'bibliometrix', CiteSpace, and Excel programs, for a meticulous examination and systematic organization of data concerning journals, authors, countries/regions, institutions, keywords, and references.
By August 31, 2023, the literature was distributed across 379 journals worldwide, authored by 4,235 individuals from 1726 institutions. It featured 2,363 keywords and 38,412 references. 'HEADACHE' led in publication count, with 'SILBERSTEIN S' as the most prolific author. The United States ranked highest in publication volume, with 'UNIV COPENHAGEN' leading among institutions.
Our research findings indicate that researchers in the field continue to maintain a focus on the calcitonin gene-related peptide (CGRP) system and explore diverse mechanisms for drug development through the application of novel biotechnological approaches. Furthermore, it is imperative to enhance the assessment of clinical trial outcomes, consistently monitor the efficacy and safety of prominent drugs such as Erenumab and Fremanezumab. There is a need for further evaluation of acute and preventive treatments tailored to different populations and varying types of migraine.
偏头痛给全球带来了沉重负担，影响着患者和社会。药物治疗作为主要治疗方法，会带来特定的不良反应。强调这些反应对于改进治疗策略和提高患者福祉至关重要。因此，我们对相关文献进行了全面的文献计量学和可视化分析。
我们在科学网的科学引文索引扩展版中进行了全面搜索，根据文献类型、出版日期和语言等标准限制用于分析的文献。随后，我们使用了各种分析工具，包括VOSviewer、Scimago Graphica、R包“bibliometrix”、CiteSpace和Excel程序，对有关期刊、作者、国家/地区、机构、关键词和参考文献的数据进行细致检查和系统整理。
截至2023年8月31日，文献分布在全球379种期刊上，由来自1726个机构的4235人撰写。它有2363个关键词和38412条参考文献。《头痛》在发表数量上领先，“西尔伯斯坦·S”是产量最高的作者。美国在出版量方面排名最高，“哥本哈根大学”在机构中领先。
我们的研究结果表明，该领域的研究人员继续关注降钙素基因相关肽（CGRP）系统，并通过应用新型生物技术方法探索药物开发的多种机制。此外，必须加强对临床试验结果的评估，持续监测依瑞奈尤单抗和夫瑞奈尤单抗等知名药物的疗效和安全性。有必要进一步评估针对不同人群和不同类型偏头痛的急性和预防性治疗。
