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撒哈拉以南非洲农村社区糖尿病患者的胰岛素治疗:一篇综述

Insulin therapy among diabetic patients in rural communities of Sub-Saharan Africa: a perspective review.

作者信息

Kiconco Ritah, Lumumba Sylvia Achieng, Bagenda Charles Nkubi, Atwine Raymond, Ndarubweine Joseph, Rugera Simon Peter

机构信息

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara City, Mbarara-Kabale Road, Mbarara 1410, Uganda.

Department of Biochemistry, Sororti University, Soroti, Uganda.

出版信息

Ther Adv Endocrinol Metab. 2024 Feb 19;15:20420188241232280. doi: 10.1177/20420188241232280. eCollection 2024.

Abstract

In this perspective review, we describe a brief background on the status quo of diabetes mellitus-related therapies and glycemic control among patients in rural communities in sub-Saharan Africa. The article discusses insulin therapy as well as the difficulties in obtaining insulin and oral hypoglycemic medications for diabetic patients living in sub-Saharan Africa. We wrap up our discussion with suggestions on solutions and opportunities for future research to tackle this health challenge in these impoverished communities. We conducted a literature search from PubMed and Google Scholar up until August 2023. Key words were used to generate search terms used to retrieve the required information. All types of literature with pertinent information on the current topic were included in the study. Diabetes mellitus is on the rise in sub-Saharan Africa. Several studies have reported poor glycemic control, low screening rates for diabetes mellitus, cigarette smoking, high alcohol consumption, prescription of antidiabetic therapy, and associated costs as contributors to the uptake of antidiabetic treatment. Although there is paucity of data on the extent of insulin therapy uptake and its possible modifiable contributors among the diabetic patients in the region, the anticipated increase in the number of people with diabetes on the continent makes it critical for global leaders to address the research gaps in insulin therapy among rural communities of sub-Saharan Africa, thus reducing the burden of diabetes in these populations.

摘要

在这篇观点综述中,我们描述了撒哈拉以南非洲农村社区糖尿病相关治疗现状和血糖控制的简要背景。本文讨论了胰岛素治疗以及撒哈拉以南非洲糖尿病患者获取胰岛素和口服降糖药物的困难。我们以针对解决这些贫困社区这一健康挑战的解决方案和未来研究机会的建议来结束讨论。我们截至2023年8月在PubMed和谷歌学术上进行了文献检索。使用关键词生成检索词以获取所需信息。所有包含当前主题相关信息的文献类型都纳入了研究。糖尿病在撒哈拉以南非洲呈上升趋势。几项研究报告称,血糖控制不佳、糖尿病筛查率低、吸烟、高酒精消费、抗糖尿病治疗的处方以及相关成本是影响抗糖尿病治疗采用率的因素。尽管该地区糖尿病患者中胰岛素治疗采用率及其可能的可改变影响因素的数据匮乏,但该大陆糖尿病患者数量的预期增加使得全球领导人必须解决撒哈拉以南非洲农村社区胰岛素治疗方面的研究差距,从而减轻这些人群的糖尿病负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d896/10878220/09e0db7d5997/10.1177_20420188241232280-fig1.jpg

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