Safavi Amir H, Dawson Laura A, Mesci Aruz
Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.
Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Clin Transl Radiat Oncol. 2024 Feb 2;45:100740. doi: 10.1016/j.ctro.2024.100740. eCollection 2024 Mar.
•Stereotactic body radiotherapy (SBRT) is a safe and effective locoregional therapy for inoperable patients with HCC.•SBRT compares favorably with other local therapies in terms of local control, survival, morbidity, and cost-effectiveness.•SBRT should be considered and discussed in multidisciplinary management of appropriate HCC patients.•Advances in SBRT and novel combinations with systemic therapy may further widen the therapeutic index in HCC.
•立体定向体部放疗(SBRT)是一种针对无法手术的肝癌患者的安全有效的局部区域治疗方法。
•在局部控制、生存率、发病率和成本效益方面,SBRT与其他局部治疗方法相比具有优势。
•在合适的肝癌患者多学科管理中,应考虑并讨论SBRT。
•SBRT的进展以及与全身治疗的新型联合应用可能会进一步扩大肝癌的治疗指数。