Piperakis S M, McLennan A G
Mutat Res. 1985 Mar;142(3):83-5. doi: 10.1016/0165-7992(85)90044-2.
Treatment of HeLa cells with ethanol and sodium arsenite, compounds which are known to elicit the heat-shock response, before infection with UV-irradiated adenovirus 2 has been found to result in the enhanced reactivation of the damaged virus in a manner similar to that obtained by pre-irradiation or heating of the cells. Enhanced reactivation may be the result of the inhibition of DNA synthesis caused by these agents since hydroxyurea also produced a significant enhancement.
在用紫外线照射的腺病毒2感染之前,用乙醇和亚砷酸钠(已知可引发热休克反应的化合物)处理海拉细胞,已发现会导致受损病毒的再激活增强,其方式类似于通过对细胞进行预照射或加热所获得的方式。增强的再激活可能是这些试剂引起的DNA合成抑制的结果,因为羟基脲也产生了显著的增强作用。