College of Agronomy, Northwest A&F University, Xianyang, Shaanxi Province, People's Republic of China.
Maanshan Agricultural and Rural Bureau, Xianyang, Shaanxi Province, People's Republic of China.
Chirality. 2024 Feb;36(2):e23638. doi: 10.1002/chir.23638.
Chiral pesticides have the special chiral structures, so enantioselective biological effects are usually observed in living organisms. Current study used paclobutrazol as a case study and explored the enantioselective degradation and oxidative stress effect on wheat. The results demonstrated that the degradation of R-paclobutrazol was faster than S-paclobutrazol significantly and improved the content of MDA and O in wheat plants, which proved that the R-paclobutrazol induced oxidative damage in wheat, showing selective biological effects, and S-paclobutrazol was friendly to wheat. This study provided a theoretical basis for the selective activity of chiral pesticides and the development of chiral pesticide monomers.
手性农药具有特殊的手性结构，因此在生物体中通常会观察到对映选择性生物效应。本研究以多效唑为例，探讨了其对小麦的对映选择性降解和氧化应激效应。结果表明，R-多效唑的降解速度明显快于 S-多效唑，同时提高了小麦植株中 MDA 和 O 的含量，证明 R-多效唑诱导了小麦的氧化损伤，表现出选择性生物效应，而 S-多效唑则对小麦友好。该研究为手性农药的选择性活性和手性农药单体的开发提供了理论依据。
