[质子束放疗：先进质子放疗技术的原理与设计]

[pMBRT: Principles and Design of Advanced Proton Radiotherapy Techniques].

作者信息

Wang Xiaowa, Du Ning, Wang Lan

机构信息

Shanghai Proton and Heavy Ion Center, Shanghai, 201321.

Shanghai Key Laboratory of Radiation Oncology, Shanghai, 201321.

出版信息

Zhongguo Yi Liao Qi Xie Za Zhi. 2024 Jan 30;48(1):10-14. doi: 10.3969/j.issn.1671-7104.230208.

DOI:10.3969/j.issn.1671-7104.230208

PMID:38384210

Abstract

The development history of pMBRT, the biological role of minibeam, the mechanism of minibeam protection of tissues, the generation of minibeam (collimator method and magnetic focusing method), and the analysis of advantages and disadvantages of proton minibeam matrix arrays is introduced with advanced proton minibeam arrays (pMBRT). It is proposed that the combination of proton minibeam arrays and magnetic resonance fields can help to exploit the normal tissue protective function of pMBRT, and improve the precision of proton therapy.

摘要

本文通过先进的质子微束阵列（pMBRT）介绍了质子微束放射治疗（pMBRT）的发展历史、微束的生物学作用、组织微束保护机制、微束的产生（准直器法和磁聚焦法）以及质子微束矩阵阵列的优缺点分析。提出质子微束阵列与磁共振场相结合有助于发挥pMBRT的正常组织保护功能，并提高质子治疗的精度。