Feldon S E, Lee C P, Muramatsu S K, Weiner J M
Arch Ophthalmol. 1985 Feb;103(2):213-5. doi: 10.1001/archopht.1985.01050020065021.
Quantitative assessment of computed tomographic (CT) scans was performed on 98 orbits of 49 patients with Graves' ophthalmopathy. Extraocular muscle volume and orbital fat volume were determined, according to whether optic neuropathy was absent, had developed during follow-up, or was present at the time of scanning. No differences in muscle volume were found between the group already having optic neuropathy and the group in which optic neuropathy developed during follow-up. Both optic neuropathy groups, however, had significant increases in extraocular muscle volume compared with the group without optic neuropathy. The absolute amount of orbital fat was the same for all groups, but the relative amount of orbital fat tended to decrease as total orbital volume increased with development or presence of optic neuropathy. This study establishes a quantitative relationship between optic neuropathy and extraocular muscle enlargement in Graves' ophthalmopathy. Orbital fat, however, does not play an important role in the disease.
对49例格雷夫斯眼病患者的98个眼眶进行了计算机断层扫描（CT）的定量评估。根据是否存在视神经病变、随访期间是否发生视神经病变或扫描时是否存在视神经病变，测定眼外肌体积和眼眶脂肪体积。在已经患有视神经病变的组和随访期间发生视神经病变的组之间，未发现肌肉体积有差异。然而，与没有视神经病变的组相比，两个视神经病变组的眼外肌体积均显著增加。所有组的眼眶脂肪绝对量相同，但随着视神经病变的发展或存在，眼眶总体积增加，眼眶脂肪的相对量趋于减少。本研究建立了格雷夫斯眼病视神经病变与眼外肌增大之间的定量关系。然而，眼眶脂肪在该疾病中并不起重要作用。
