Kale Prathamesh, Shrivastava Sandeep, Pundkar Aditya, Balusani Prashanth
Orthopaedic Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Orthopaedics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2024 Jan 22;16(1):e52722. doi: 10.7759/cureus.52722. eCollection 2024 Jan.
This comprehensive review explores the applications of platelet-rich plasma (PRP) in the context of compound fracture care, providing a thorough examination of its biological mechanisms, preparation techniques, and clinical implications. The analysis highlights PRP's potential in accelerating bone healing, enhancing soft tissue repair, reducing inflammation and infection risks, and managing pain during fracture recovery. The review underscores the importance of ethical and regulatory considerations in integrating PRP into orthopaedic practice, emphasising informed consent, transparent patient communication, and ongoing monitoring of ethical concerns. Looking ahead, the implications for the future of compound fracture care suggest a transformative shift with the potential for personalised medicine approaches and emerging technologies. However, the conclusion calls for a balanced perspective, acknowledging the promising applications of PRP while emphasising the need for responsible and ethical use. The collaborative efforts of healthcare professionals, researchers, and regulatory bodies are crucial in navigating this evolving landscape and harnessing the healing power of PRP to redefine orthopaedic care for individuals with compound fractures.
本综述全面探讨了富血小板血浆(PRP)在复合骨折护理中的应用,深入研究了其生物学机制、制备技术及临床意义。分析强调了PRP在加速骨折愈合、促进软组织修复、降低炎症和感染风险以及控制骨折恢复期间疼痛方面的潜力。该综述强调了在将PRP纳入骨科实践时,伦理和监管考量的重要性,强调了知情同意、与患者的透明沟通以及对伦理问题的持续监测。展望未来,复合骨折护理的前景暗示着一种变革性转变,具有个性化医疗方法和新兴技术的潜力。然而,结论呼吁保持平衡的观点,在认可PRP有前景的应用的同时,强调负责任和符合伦理使用的必要性。医疗保健专业人员、研究人员和监管机构的共同努力对于应对这一不断变化的局面以及利用PRP的愈合能力重新定义复合骨折患者的骨科护理至关重要。