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伪装成小脑幕脑膜瘤的硬脑膜型大B细胞淋巴瘤。

Dural-based large B-cell lymphoma masquerading as a tentorial meningioma.

作者信息

Inami Kasumi, Tsutsumi Satoshi, Hashizume Akane, Yamataka Motoki, Sugiyama Natsuki, Ueno Hideaki, Ishii Hisato

机构信息

Department of Neurological Surgery, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.

Department of Pathology, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.

出版信息

Radiol Case Rep. 2024 Feb 13;19(5):1661-1665. doi: 10.1016/j.radcr.2024.01.058. eCollection 2024 May.

DOI:10.1016/j.radcr.2024.01.058
PMID:38384697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10876468/
Abstract

A 53-year-old woman presented with a 2-week history of headache and vertigo. Computed tomography revealed a hyperdense tumor, measuring 30 × 31 × 36 mm in diameter, in the anteromedial parts of the cerebellar hemispheres. Cerebral magnetic resonance imaging 10 days later revealed an apparent extra-axial tumor with broad attachment to the medial tentorium cerebelli and rapid growth to a diameter of 40 × 41 × 46 mm. Cerebral angiography revealed no obvious feeding vessels or tumor stains. The patient underwent biopsy through the left occipital transtentorial route. The histological appearance was consistent with diffuse large B-cell lymphoma. Intracranial lymphoma may present as a dural tumor that mimics a meningioma. Rapid tumor growth incongruous with benign meningiomas should be assumed to be possible lymphoma, and prompt biopsy should be performed.

摘要

一名53岁女性,有2周的头痛和眩晕病史。计算机断层扫描显示在小脑半球前内侧部分有一个直径为30×31×36mm的高密度肿瘤。10天后的脑磁共振成像显示一个明显的轴外肿瘤,与小脑幕内侧广泛相连,并迅速生长至直径40×41×46mm。脑血管造影未发现明显的供血血管或肿瘤染色。患者通过左枕部经小脑幕入路进行了活检。组织学表现符合弥漫性大B细胞淋巴瘤。颅内淋巴瘤可能表现为类似脑膜瘤的硬脑膜肿瘤。与良性脑膜瘤不符的肿瘤快速生长应考虑可能为淋巴瘤,并应及时进行活检。

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本文引用的文献

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A Meningioma Mimic and Distinct Subtype of Primary Central Nervous System Lymphoma: Primary Dural Lymphoma.原发性中枢神经系统淋巴瘤的一种脑膜瘤样且独特的亚型:原发性硬脑膜淋巴瘤。
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Primary dural lymphoma: Case report.原发性硬脑膜淋巴瘤:病例报告
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Dural-based lesions: is it a meningioma?硬脑膜起源性病变:是脑膜瘤吗?
Neuroradiology. 2021 Aug;63(8):1215-1225. doi: 10.1007/s00234-021-02632-y. Epub 2021 Jan 18.
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Multi-marker algorithms based on CXCL13, IL-10, sIL-2 receptor, and β2-microglobulin in cerebrospinal fluid to diagnose CNS lymphoma.基于 CXCL13、IL-10、sIL-2 受体和β2-微球蛋白的脑脊液多标志物算法诊断中枢神经系统淋巴瘤。
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Small Cell Variant of Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma of the Dura Mimicking Tentorial Meningioma.硬脑膜间变性大细胞淋巴瘤伴间变性淋巴瘤激酶阳性小细胞变异型,酷似小脑幕脑膜瘤。
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Glioblastoma Mimicking Meningioma: Report of 2 Cases.酷似脑膜瘤的胶质母细胞瘤:2例报告
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J Neuroophthalmol. 2012 Sep;32(3):240-2. doi: 10.1097/WNO.0b013e31825103a5.