Kensil C R, Dennis E A
Lipids. 1985 Feb;20(2):80-3. doi: 10.1007/BF02534212.
Phospholipase A2 (Naja naja naja) catalyzes the hydrolysis of dipalmitoyl phosphatidylcholine in small unilamellar vesicles (SUVs) with a faster initial rate than in large unilamellar vesicles (LUVs) and multilamellar vesicles (MLVs). For the SUVs, the hydrolysis was initially faster for gel phase than liquid crystalline phase phospholipid. For both LUVs and MLVs, hydrolysis was low except in a small temperature range around the thermotropic phase transition of the phospholipid. In this temperature range, the reaction time course of phospholipase action on dipalmitoyl phosphatidylcholine in LUVs and MLVs included a lag period. With SUVs, a lag period also was observed above the phase transition temperature, but it was not observed below it.
磷脂酶A2（眼镜蛇指名亚种）催化小单层囊泡（SUVs）中二月桂酰磷脂酰胆碱的水解反应，其初始反应速率比在大单层囊泡（LUVs）和多层囊泡（MLVs）中更快。对于SUVs，凝胶相磷脂的水解初始速率比液晶相磷脂更快。对于LUVs和MLVs，除了在磷脂热致相变附近的小温度范围内，水解反应速率较低。在这个温度范围内，磷脂酶作用于LUVs和MLVs中二月桂酰磷脂酰胆碱的反应时间进程包括一个延迟期。对于SUVs，在相变温度以上也观察到了延迟期，但在相变温度以下未观察到。
