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低血糖恐惧、治疗依从性与 2 型糖尿病患者生活质量及其决定因素

Hypoglycaemia fear, treatment adherence, and the quality of life in patients with type 2 diabetes and its determinants.

机构信息

Department of Nursing, Faculty of Health Sciences, Istanbul Aydin University, Istanbul, Turkey.

Department of Midwifery, Hamidiye Faculty of Health Sciences, Public Health Nursing, University of Health Sciences, Istanbul, Turkey.

出版信息

Int J Nurs Pract. 2024 Apr;30(2):e13248. doi: 10.1111/ijn.13248. Epub 2024 Feb 22.

Abstract

AIM

This work aims to evaluate the relationship between the fear of hypoglycaemia, treatment adherence, and the quality of life in patients with type 2 diabetes mellitus (T2DM) and its determinants.

METHODS

This descriptive and cross-sectional study sample recruited 1060 T2DM outpatients in a health centre between January and July 2022. The Hypoglycemia Fear Survey (HFS), Type 2 DM Treatment Patient Compliance Scale, and the 5-Level EuroQol 5-Dimension (EQ-5D-5L) were used for data collection.

RESULTS

There was a positive correlation between age, duration of T2DM, and the scores obtained from the HFS and its subscales (p < 0.001). There was a positive, moderate correlation between the total HFS score and the TCS (p < 0.001). There was a negative correlation between the scores obtained from the HFS and the EQ-5D-5L (p < 0.001). The multiple regression analysis showed that the quality of life scores of the patients were significantly predicted by hypoglycaemia fear, duration of T2DM diagnosis, and age. (F = 91.691, p < 0.001). Hypoglycaemia fear, duration of T2DM diagnosis, and age explained 38.1% of the quality of life of patients.

CONCLUSION

We determined that the increase in hypoglycaemia fear resulted in a decrease in treatment adherence. Besides, hypoglycaemia fear increased with increasing age and duration of T2DM diagnosis.

摘要

目的

本研究旨在评估 2 型糖尿病(T2DM)患者的低血糖恐惧、治疗依从性与生活质量之间的关系及其决定因素。

方法

本描述性和横断面研究于 2022 年 1 月至 7 月在一家医疗中心招募了 1060 名 T2DM 门诊患者。使用低血糖恐惧调查(HFS)、2 型糖尿病治疗患者依从性量表和 5 级欧洲五维健康量表(EQ-5D-5L)进行数据收集。

结果

年龄、T2DM 病程与 HFS 及其各分量表评分呈正相关(p<0.001)。HFS 总分与 TCS 呈正相关,相关性中等(p<0.001)。HFS 评分与 EQ-5D-5L 呈负相关(p<0.001)。多元回归分析显示,患者的生活质量评分显著受低血糖恐惧、T2DM 诊断持续时间和年龄的预测(F=91.691,p<0.001)。低血糖恐惧、T2DM 诊断持续时间和年龄解释了患者生活质量的 38.1%。

结论

我们发现低血糖恐惧的增加导致治疗依从性下降。此外,低血糖恐惧随 T2DM 诊断持续时间和年龄的增加而增加。

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