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恶性输尿管梗阻:初次输尿管支架置入失败后,8Fr 与 6Fr 金属及塑料输尿管支架的比较。

Malignant ureteral obstruction: comparison of metallic, 8 French and 6 French ureteric stents after failure of initial ureteric stent.

机构信息

Department of Urology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.

出版信息

World J Urol. 2024 Feb 22;42(1):92. doi: 10.1007/s00345-024-04803-x.

DOI:10.1007/s00345-024-04803-x
PMID:38386090
Abstract

PURPOSE

Malignant ureteric obstruction is a significant management challenge. The failure of ureteric stents often leads to long-term nephrostomy tubes. This is delayed for as long as possible due to its' associated morbidity. Several types of ureteric stents are available, however there is little evidence demonstrating which stents are better for preventing progression to nephrostomy tubes. This study looked to determine whether a new 6 French (Fr) polymer stent, 8Fr polymer stent or metallic stent achieved a longer functional duration once the initial polymer ureteric stent failed.

METHODS

A retrospective, longitudinal study was performed at a single tertiary institution. All patients who underwent ureteric stenting with a 6Fr polymer stent for malignancy between 2010 and 2020 were included. Patients were followed up until death with ureteric stent in situ or permanent nephrostomy tube insertion.

RESULTS

A total of 46 patients (66 ureters) had ureteric stents inserted for malignancy. From initial ureteric stent failure, 10 stents were changed to a new 6Fr polymer stent, 42 were changed to an 8Fr polymer stent and 14 were changed to a Resonance® 6Fr metallic stent. The Resonance 6Fr metallic stent had the longest median functional duration of 14 months (p = 0.012).

CONCLUSION

Resonance® 6Fr metallic stents appear to have a significantly longer functional duration than a new 6Fr polymer stent or 8Fr polymer stent, which may allow patients to enjoy a better quality of life and delay permanent nephrostomy tube insertion.

摘要

目的

恶性输尿管梗阻是一个重大的管理挑战。输尿管支架的失败往往导致长期的肾造瘘管。由于其相关的发病率,这种情况被尽可能地延迟。有几种类型的输尿管支架可供选择,但几乎没有证据表明哪种支架更能防止进展为肾造瘘管。本研究旨在确定新型 6Fr(French,Fr)聚合物支架、8Fr 聚合物支架或金属支架在初始聚合物输尿管支架失败后是否能实现更长的功能持续时间。

方法

在一家单一的三级医疗机构进行了回顾性、纵向研究。纳入 2010 年至 2020 年间因恶性肿瘤接受 6Fr 聚合物输尿管支架置入术的所有患者。患者在输尿管支架原位或永久性肾造瘘管插入的情况下,直至死亡进行随访。

结果

共有 46 名患者(66 侧输尿管)因恶性肿瘤接受输尿管支架置入术。从初始输尿管支架失败开始,10 个支架更换为新型 6Fr 聚合物支架,42 个更换为 8Fr 聚合物支架,14 个更换为 Resonance® 6Fr 金属支架。Resonance 6Fr 金属支架的中位功能持续时间最长,为 14 个月(p=0.012)。

结论

Resonance® 6Fr 金属支架的功能持续时间似乎明显长于新型 6Fr 聚合物支架或 8Fr 聚合物支架,这可能使患者享有更好的生活质量,并延迟永久性肾造瘘管插入。

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BJUI Compass. 2020 Apr 22;1(2):74-81. doi: 10.1002/bco2.14. eCollection 2020 May.
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Use of metallic and polymeric ureteral stents in malignant ureteral obstruction.
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BJUI Compass. 2020 Oct 15;2(1):58-63. doi: 10.1002/bco2.51. eCollection 2021 Jan.
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