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双 J 金属网输尿管支架治疗恶性输尿管梗阻的疗效:一项回顾性研究。

Effectiveness of Double-J Metallic Mesh Ureteral Stents for Malignant Ureteral Obstruction: A Retrospective Study.

机构信息

Department of Urology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.

Department of Urology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan

出版信息

In Vivo. 2023 Mar-Apr;37(2):806-810. doi: 10.21873/invivo.13145.

DOI:10.21873/invivo.13145
PMID:36881102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10026648/
Abstract

BACKGROUND/AIM: Malignant ureteral obstruction is associated with high rates of failure with traditional ureteral stents. Double-J metallic mesh ureteral stent is one of the latest options for treating malignant ureteral obstruction. However, data regarding the efficacy of using this stent in this context are limited. Thus, we retrospectively investigated the efficacy of this stent.

PATIENTS AND METHODS

We retrospectively analyzed the records of all patients who required double-J metallic mesh ureteral stent placement for malignant ureteral obstruction at Ishikawa Prefectural Central Hospital (Kanazawa, Japan) between October 2018 and April 2022. Primary stent patency was defined as complete or partial resolution of hydronephrosis as shown by imaging studies or successful removal of a preexisting nephrostomy tube. Stent failure was defined as unplanned stent exchange or nephrostomy tube placement for signs or symptoms of recurrent ureteral obstruction. A competing risk model was used to estimate the cumulative incidence of stent failure.

RESULTS

Double-J metallic mesh ureteral stents were placed in 63 ureters of 44 patients (13 males, 31 females). The median age of patients was 67 years (range=37-92 years). There was no grade 3 or higher complications. The overall primary patency rate was 95% (60 ureters). Stent failure occurred in seven patients (11%) during follow-up. The cumulative incidence of stent failure at 12 months after placement was 17.3%.

CONCLUSION

Double-J metallic mesh ureteral stent is a safe, simple, and promising treatment option for malignant ureteral obstruction.

摘要

背景/目的:传统输尿管支架治疗恶性输尿管梗阻失败率较高。双 J 型金属网输尿管支架是治疗恶性输尿管梗阻的最新选择之一。然而,关于在这种情况下使用这种支架的疗效的数据有限。因此,我们回顾性地研究了这种支架的疗效。

患者和方法

我们回顾性分析了 2018 年 10 月至 2022 年 4 月期间在石川県立中央病院(金沢市,日本)因恶性输尿管梗阻需要放置双 J 型金属网输尿管支架的所有患者的记录。主要支架通畅性定义为影像学检查显示完全或部分解除肾盂积水或成功取出先前存在的肾造瘘管。支架失败定义为计划外更换支架或放置肾造瘘管以治疗复发性输尿管梗阻的症状或体征。使用竞争风险模型估计支架失败的累积发生率。

结果

63 根输尿管的 44 名患者(13 名男性,31 名女性)中放置了双 J 型金属网输尿管支架。患者的中位年龄为 67 岁(范围=37-92 岁)。无 3 级或更高级别的并发症。总体主要通畅率为 95%(60 根输尿管)。在随访期间,7 名患者(11%)发生支架失败。放置后 12 个月时支架失败的累积发生率为 17.3%。

结论

双 J 型金属网输尿管支架是治疗恶性输尿管梗阻的一种安全、简单、有前途的治疗选择。

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World J Surg Oncol. 2019 Apr 30;17(1):74. doi: 10.1186/s12957-019-1608-6.
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Treatment outcomes of ureteral stenting for malignant extrinsic ureteral obstruction: a comparison between polymeric and metallic stents.恶性输尿管外梗阻的输尿管支架置入治疗效果:聚合物支架与金属支架的比较
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Risk Factors for Primary Failure of Metallic Ureteral Stents: Experience from a Tertiary Center.金属输尿管支架初次失败的危险因素:来自三级中心的经验。
J Endourol. 2021 Jun;35(6):912-918. doi: 10.1089/end.2017.0611. Epub 2018 Feb 12.
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Outcomes of indwelling metallic stents for malignant extrinsic ureteral obstruction.留置金属支架治疗恶性输尿管外梗阻的疗效
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