Brauman A, Algom M, Gilboa Y, Ramot Y, Golik A, Stryjer D
Br Heart J. 1985 Apr;53(4):374-7. doi: 10.1136/hrt.53.4.374.
The prevalence of mitral valve prolapse was investigated in 126 patients with hyperthyroidism due to Graves' disease or toxic nodular goitre and that of hyperthyroidism in 64 patients with mitral valve prolapse. One hundred and eleven asymptomatic healthy subjects comprised a control group. The patients with hyperthyroidism were divided into those with Graves' disease and those with toxic nodular goitre. Of the group as whole, 12 (9.5%) patients had mitral valve prolapse compared with six (5.4%) in the control group, but the difference was not statistically significant. The prevalence of mitral valve prolapse in the patients with toxic goitre was also not significantly different from that in the controls. When the prevalence in the group with Graves' disease was compared with that in the control group (16.3% vs 5.4%) the difference was significant. Only one patient with mitral valve prolapse had hyperthyroidism.
对126例由格雷夫斯病或毒性结节性甲状腺肿引起的甲状腺功能亢进患者的二尖瓣脱垂患病率进行了调查,并对64例二尖瓣脱垂患者的甲状腺功能亢进患病率进行了调查。111名无症状健康受试者组成了一个对照组。甲状腺功能亢进患者被分为格雷夫斯病患者和毒性结节性甲状腺肿患者。在整个组中,12例(9.5%)患者有二尖瓣脱垂,而对照组为6例(5.4%),但差异无统计学意义。毒性甲状腺肿患者的二尖瓣脱垂患病率与对照组也无显著差异。当将格雷夫斯病组的患病率与对照组的患病率进行比较时(16.3%对5.4%),差异具有统计学意义。只有1例二尖瓣脱垂患者患有甲状腺功能亢进。