继发性淋巴瘤中的染色体变化。
Chromosome changes in a secondary lymphoma.
作者信息
Kakati S, Kowalczyk J R, Becher R, Sandberg A A
出版信息
Cancer Genet Cytogenet. 1985 May;17(1):29-34. doi: 10.1016/0165-4608(85)90098-6.
A case of probable secondary lymphoma, poorly differentiated lymphocytic lymphoma (PDLL), is described in which two chromosomal translocations were observed, i.e., t(10;19)(q11;q13) and t(1;6)(q21;p11.1-2). A consistent numerical aberration was monosomy of chromosome #21. Accumulation of more data on secondary lymphomas is necessary in order to reach a general conclusion as to whether or not there are any nonrandom chromosomal aberrations that differentiate primary from secondary lymphomas.
本文描述了一例可能的继发性淋巴瘤，即低分化淋巴细胞淋巴瘤（PDLL），其中观察到两种染色体易位，即t(10;19)(q11;q13)和t(1;6)(q21;p11.1-2)。一个一致的数值异常是21号染色体单体性。为了得出关于是否存在任何区分原发性和继发性淋巴瘤的非随机染色体异常的一般性结论，有必要积累更多关于继发性淋巴瘤的数据。
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