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接受侵入性尿动力学检查患者的尿路感染:印度东部一家三级医疗中心的前瞻性观察研究

Urinary Tract Infections in Patients Undergoing Invasive Urodynamic Study: A Prospective Observational Study at a Tertiary Care Centre in Eastern India.

作者信息

Upadhyay Rohit, Mahmood Khalid, Tiwari Rajesh K, Raj Ankit

机构信息

Department of Urology, Indira Gandhi Institute of Medical Sciences, Patna, IND.

出版信息

Cureus. 2024 Jan 23;16(1):e52801. doi: 10.7759/cureus.52801. eCollection 2024 Jan.

Abstract

OBJECTIVE

The aim of the study was to find the estimate of the prevalence of urinary tract infections following invasive urodynamic studies (UDS) in a hospital setup and to identify the risk factors related to it.

METHOD

A total of 100 patients were enrolled in this prospective observational study after standard preoperative work, which included both urine analysis and culture procedure. The study was carried out from April 2022 to April 2023 at the Department of Urology, Indira Gandhi Institute of Medical Sciences, India. Three days following the UDS test, all the patients underwent repeat urine analysis and culture, besides screening for any lower urinary tract symptoms, abdominal pain, and fever.

RESULT

Among all, 14 patients (i.e., 6.1% of 85 individuals) had significant bacteriuria, and six patients (4.7%) developed symptoms of UTI. However, a strong association was observed between the maximal detrusor pressure during voiding (Pdet at Q max) and post-void residue (PVR), which were >20 mL before UDS, along with positive urine cultures after UDS, which was significant at <0.05.

CONCLUSION

The study demonstrated that the risk of UTIs with this diagnostic technique is minimal and that prophylactic antibiotic medication is not necessary prior to UDS in all patients.

摘要

目的

本研究旨在评估医院环境下侵入性尿动力学检查(UDS)后尿路感染的患病率,并确定与之相关的危险因素。

方法

在完成包括尿液分析和培养程序在内的标准术前准备工作后,共有100名患者纳入了这项前瞻性观察性研究。该研究于2022年4月至2023年4月在印度英迪拉·甘地医学科学研究所泌尿外科进行。在UDS检查后三天,除了筛查任何下尿路症状、腹痛和发热外,所有患者均接受了重复尿液分析和培养。

结果

在所有患者中,14名患者(即85名个体中的6.1%)有显著菌尿,6名患者(4.7%)出现了UTI症状。然而,观察到排尿时最大逼尿肌压力(Q max时的Pdet)与残余尿量(PVR)之间存在密切关联,在UDS前PVR>20 mL,且UDS后尿培养呈阳性,差异有统计学意义(<0.05)。

结论

该研究表明,采用这种诊断技术发生UTIs的风险极小,并非所有患者在UDS前都需要预防性使用抗生素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad4/10882255/9aa8ea9fd6b9/cureus-0016-00000052801-i01.jpg

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