良性前列腺增生患者尿动力学特征与症状评分及超声参数的相关性研究。

Study of correlation of urodynamic profile with symptom scoring and ultrasonographic parameters in patients with benign prostatic hyperplasia.

作者信息

Garg Ankur, Bansal Shweta, Saha Sudipta, Kumar Ajay

机构信息

Department of General Surgery, VMMC and Safdarjung Hospital, New Delhi, India.

Department of Anaesthesia, Lady Hardinge Medical College, New Delhi, India.

出版信息

J Family Med Prim Care. 2020 Jan 28;9(1):215-220. doi: 10.4103/jfmpc.jfmpc_698_19. eCollection 2020 Jan.

DOI:10.4103/jfmpc.jfmpc_698_19

PMID:32110593

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7014908/

Abstract

CONTEXT

Urodynamic study (UDS) and ultrasonography (USG) both are established investigations to assess the patients of benign prostatic hyperplasia (BPH). It is known that the prostate mass (PM) and post-void residual urine volume (PVR) are not significantly related to the patients' symptoms and degree of obstruction; however, the relation between the UDS, USG and patient's International Prostate Symptom Scoring (IPSS) has not been defined.

AIMS

To correlate the urodynamic parameters with IPSS, PM and PVR in patients with lower urinary tract symptoms (LUTS) suggestive of BPH.

SETTINGS AND DESIGN

An observational study carried out as a thesis project.

METHODS AND MATERIALS

Thirty male patients aged more than 40 years with LUTS suggestive of BPH were selected and underwent USG, UDS and IPSS. In UDS, the parameters studied were the maximum flow rate (Q), detrusor pressure (P) and bladder compliance (BC). PM and PVR were studied in the USG.

STATISTICAL ANALYSIS USED

IBM Statistical Package for the Social Sciences (SPSS) software version 16 (SPSS Inc., Chicago, USA). Pearson's correlation and two-sided significance levels were determined.

RESULTS

Significant negative correlation between Q and PVR ( = -0.404, = 0.027); PM ( = -0.655, = <0.001) and IPSS ( = -0.563, = 0.001). 2. Significant positive correlation between P and PVR ( = 0.535, = 0.002); PM ( = 0.719, = <0.001) and IPSS ( = 0.649, = <0.001). 3. Significant negative correlation between BC and PVR ( = -0.490, = 0.006); PM ( = -0.654, = <0.001) and IPSS ( = -0.667, = <0.001).

CONCLUSIONS

UDS has a significant correlation with IPSS and USG findings and urodynamic parameters give a more specific diagnosis in BPH patients when it is combined with USG and IPSS.

摘要

背景

尿动力学研究（UDS）和超声检查（USG）都是评估良性前列腺增生（BPH）患者的既定检查方法。已知前列腺体积（PM）和排尿后残余尿量（PVR）与患者症状及梗阻程度无显著相关性；然而，UDS、USG与患者国际前列腺症状评分（IPSS）之间的关系尚未明确。

目的

将尿动力学参数与提示BPH的下尿路症状（LUTS）患者的IPSS、PM和PVR进行关联分析。

设置与设计

作为一项论文项目开展的观察性研究。

方法与材料

选取30例年龄超过40岁、有提示BPH的LUTS的男性患者，进行USG、UDS及IPSS评估。在尿动力学检查中，研究的参数包括最大尿流率（Q）、逼尿肌压力（P）和膀胱顺应性（BC）。在超声检查中研究PM和PVR。

所用统计分析方法

美国芝加哥SPSS公司的IBM社会科学统计软件包（SPSS）第16版。确定Pearson相关性及双侧显著性水平。

结果

Q与PVR之间存在显著负相关（r = -0.404，P = 0.027）；与PM之间存在显著负相关（r = -0.655，P = <0.001），与IPSS之间存在显著负相关（r = -0.563，P = 0.001）。2. P与PVR之间存在显著正相关（r = 0.535，P = 0.002）；与PM之间存在显著正相关（r = 0.719，P = <0.001），与IPSS之间存在显著正相关（r = 0.649，P = <0.001）。3. BC与PVR之间存在显著负相关（r = -0.490，P = 0.006）；与PM之间存在显著负相关（r = -0.654，P = <0.001），与IPSS之间存在显著负相关（r = -0.667，P = <0.001）。