Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing, Dongcheng, Beijing, 100730, China.
Eur J Clin Microbiol Infect Dis. 2017 Oct;36(10):1873-1878. doi: 10.1007/s10096-017-3007-7. Epub 2017 Jun 2.
The purpose of this study was to investigate the incidence and risk factors of male urinary tract infection (UTI) after urodynamic study (UDS). A total of 854 consecutive male patients, who underwent UDS at Peking Union Medical College Hospital from January 2010 to March 2016, were recruited in this study. Two to four weeks before the examination, urinalysis with bacterial culture was performed. Patients with negative results were selected for UDS. Immediately before the examination, urinalysis was repeated to rule out any preoperative UTI. Between 48 and 72 h after the exam, urine culture was performed again to determine the incidence of UTI. The incidence of UTI and patients' baseline characteristics, including age, medical history, urodynamic parameters, current diagnosis and pathogen type, were analyzed. Among the 854 patients undergoing UDS, urinary infection was found in 84 cases after the examination, the incidence was 9.83%. Comorbidity with diabetes, post void residual (PVR), volume of prostate (Vp), and two urodynamic parameters, maximal flow rate (Qmax) and average flow rate (Qav) were found to be the independent risk factors for UTI after UDS. The most common pathogens were Escherichia coli (54.76%) and Enterococcus faecalis (19.05%). The incidence of UTI after UDS in male patients was 9.83%. Patients who suffered from comorbidity of diabetes, high PVR, high Vp, low Qmax or Qav may need to be treated with prophylactic antibiotics to prevent postoperative UTI.
本研究旨在探讨尿动力学检查（UDS）后男性尿路感染（UTI）的发生率及危险因素。2010 年 1 月至 2016 年 3 月，共招募了 854 例连续接受 UDS 的男性患者。在检查前 2-4 周，进行尿分析和细菌培养。选择结果为阴性的患者进行 UDS。在检查前，再次进行尿分析以排除任何术前 UTI。在检查后 48-72 小时，再次进行尿液培养以确定 UTI 的发生率。分析 UTI 的发生率和患者的基线特征，包括年龄、病史、尿动力学参数、当前诊断和病原体类型。在 854 例接受 UDS 的患者中，有 84 例在检查后出现尿路感染，发生率为 9.83%。合并糖尿病、剩余尿量（PVR）、前列腺体积（Vp）、两个尿动力学参数（最大尿流率[Qmax]和平均尿流率[Qav]）是 UDS 后发生 UTI 的独立危险因素。最常见的病原体是大肠埃希菌（54.76%）和粪肠球菌（19.05%）。男性患者 UDS 后 UTI 的发生率为 9.83%。患有糖尿病合并症、高 PVR、高 Vp、低 Qmax 或 Qav 的患者可能需要预防性使用抗生素来预防术后 UTI。
