Chandra Rudrika, Kumari Sarita, Bhatla Neerja, Kumar Rakesh, Tiwari Abhinav, Sachani Hemant, Kumar Lalit
Department of Obstetrics and Gynaecology, Division of Gynaecologic Oncology, All India Institute of Medical Sciences, New Delhi, India.
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Nucl Med. 2023 Oct-Dec;38(4):366-375. doi: 10.4103/ijnm.ijnm_42_22. Epub 2023 Dec 20.
Ovarian cancer (OC) is the most lethal gynecological malignancy with majority of cases diagnosed in advanced stages and associated with high morbidity and mortality. Positron emission tomography/computed tomography (PET/CT) has emerged as an integral part of the management of several nongynecological cancers. We used PubMed search engine using MeSH words "ovarian cancer" and "PET/CT" and reviewed the current status of PET/CT in epithelial OC. Its application related to ovarian tumor including adnexal mass evaluation, baseline staging, as a triaging tool for upfront surgery or neoadjuvant chemotherapy, for response assessment and prognostication, and for relapse detection and treatment planning has been highlighted. we highlight the current guidelines and newer upcoming PET modalities and radiotracers.
卵巢癌(OC)是最致命的妇科恶性肿瘤,大多数病例在晚期被诊断出来,且发病率和死亡率都很高。正电子发射断层扫描/计算机断层扫描(PET/CT)已成为几种非妇科癌症管理中不可或缺的一部分。我们使用PubMed搜索引擎,以医学主题词“卵巢癌”和“PET/CT”进行检索,并回顾了PET/CT在上皮性OC中的现状。重点介绍了其在卵巢肿瘤中的应用,包括附件包块评估、基线分期、作为 upfront 手术或新辅助化疗的分诊工具、用于疗效评估和预后判断,以及用于复发检测和治疗规划。我们还强调了当前的指南以及新出现的PET模式和放射性示踪剂。