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一名青少年转移性滋养细胞肿瘤的罕见病例,表现为弥漫性囊性肺疾病和肺动脉假性动脉瘤。

An unusual case of metastatic trophoblastic neoplasm presenting with diffuse cystic lung disease and pulmonary artery pseudoaneurysms in a teenager.

作者信息

Guler Sevim, Hull Nathan C, Arteta Manuel, Allen-Rhoades Wendy, Shahi Maryam, Ishitani Michael B, Demirel Nadir

机构信息

Istanbul University-Cerrahpasa School of Medicine, Istanbul, Turkey.

Division of Pediatric Radiology, Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Pediatr Pulmonol. 2024 May;59(5):1482-1486. doi: 10.1002/ppul.26936. Epub 2024 Feb 23.

Abstract

Diffuse cystic lung diseases (DCLDs) are a diverse group of lung disorders characterized by the presence of multiple air filled cysts within the lung tissue. These cysts are thin walled and surrounded by normal lung tissue. In adults, DCLD can be associated with various conditions such as lymphangioleiomyomatosis (LAM), Langerhans cell histiocytosis, cancers, and more. In children, DCLD is often linked to lung developmental abnormalities, with bronchopulmonary dysplasia being a common cause. Patients with pulmonary cysts are typically asymptomatic, but some may experience mild symptoms or pneumothorax. While DCLD in children is rarely due to malignancy, metastatic lung disease can be a cause. It is important for clinicians to be aware of the possibility of metastatic lung disease when encountering DCLD.

摘要

弥漫性囊性肺疾病(DCLD)是一组多样的肺部疾病,其特征是肺组织内存在多个含气囊肿。这些囊肿壁薄,周围是正常肺组织。在成人中,DCLD可与多种病症相关,如淋巴管平滑肌瘤病(LAM)、朗格汉斯细胞组织细胞增多症、癌症等。在儿童中,DCLD常与肺发育异常有关,支气管肺发育不良是常见原因。肺囊肿患者通常无症状,但有些可能会出现轻微症状或气胸。虽然儿童DCLD很少由恶性肿瘤引起,但转移性肺病可能是一个原因。临床医生在遇到DCLD时,意识到转移性肺病的可能性很重要。

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