Fielli Mariano, Avila Fabio, Saino Agustina, Seimah Deborah, Fernández Casares Marcelo
Pulmonary Section, Department of Internal Medicine, Hospital Nacional Posadas, Buenos Aires, Argentina.
Pathology Department, Hospital Nacional Posadas, Buenos Aires, Argentina.
Respir Med Case Rep. 2016 Jan 6;17:83-5. doi: 10.1016/j.rmcr.2015.12.006. eCollection 2016.
The diffuse cystic lung diseases (DCLDs) are a pathophysiologically heterogeneous processes characterized by the presence of multiple thin-walled, air-filled spaces within the pulmonary parenchyma. The most common causes of DCLD are lymphangioleiomyomatosis (LAM) and pulmonary Langerhans cell histiocytosis (PLCH). DCLD develops rarely as a result of malignancy, typically secondary to metastases from peripheral sarcomas and mesenchymal tumors. DCLD have also been reported in a variety of other metastatic disease such as adenocarcinoma. Our case describes a patient with DCLD as a result of metastatic colorectal adenocarcinoma.
弥漫性囊性肺疾病(DCLD)是一类病理生理过程异质性的疾病,其特征为肺实质内存在多个薄壁、含气腔隙。DCLD最常见的病因是淋巴管平滑肌瘤病(LAM)和肺朗格汉斯细胞组织细胞增多症(PLCH)。DCLD极少由恶性肿瘤引起,通常继发于周围肉瘤和间叶性肿瘤的转移。DCLD在其他多种转移性疾病如腺癌中也有报道。我们的病例描述了一名因转移性结直肠癌导致DCLD的患者。