Post Corine E, Bitter Thom, Briscoe Adam, van Langen Inger, Fluit René, Verdonschot Nico, Janssen Dennis
Orthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Invibio Ltd., Thornton Cleveleys FY5 4QD, Lancashire, UK.
Bioengineering (Basel). 2024 Jan 25;11(2):116. doi: 10.3390/bioengineering11020116.
Polyetheretherketone (PEEK) is of interest as implant material for cementless tibial total knee arthroplasty (TKA) components due to its potential advantages. One main advantage is that the stiffness of PEEK closely resembles the stiffness of bone, potentially avoiding peri-prosthetic stress-shielding. When introducing a new implant material for cementless TKA designs, it is essential to study its effect on the primary fixation. The primary fixation may be influenced by patient factors such as age, gender, and body mass index (BMI). Therefore, the research objectives of this finite element (FE) study were to investigate the effect of material (PEEK vs. titanium) and patient characteristics on the primary fixation (i.e., micromotions) of a cementless tibial tray component. A total of 296 FE models of 74 tibiae were created with either PEEK or titanium material properties, under gait and squat loading conditions. Overall, the PEEK models generated larger peak micromotions than the titanium models. Differences were seen in the micromotion distributions between the PEEK and titanium models for both the gait and squat models. The micromotions of all tibial models significantly increased with BMI, while gender and age did not influence micromotions.
聚醚醚酮（PEEK）因其潜在优势而成为非骨水泥型胫骨全膝关节置换术（TKA）组件的植入材料。一个主要优点是PEEK的刚度与骨的刚度非常相似，有可能避免假体周围的应力遮挡。在为非骨水泥型TKA设计引入新的植入材料时，研究其对初始固定的影响至关重要。初始固定可能会受到年龄、性别和体重指数（BMI）等患者因素的影响。因此，这项有限元（FE）研究的目的是调查材料（PEEK与钛）和患者特征对非骨水泥型胫骨托组件初始固定（即微动）的影响。在步态和深蹲加载条件下，使用PEEK或钛材料属性创建了总共74个胫骨的296个有限元模型。总体而言，PEEK模型产生的峰值微动比钛模型更大。在步态和深蹲模型中，PEEK和钛模型的微动分布存在差异。所有胫骨模型的微动都随BMI显著增加，而性别和年龄对微动没有影响。
