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医生估计与心房颤动患者报告的健康状况。

Physician Estimates and Patient-Reported Health Status in Atrial Fibrillation.

机构信息

Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.

University of Missouri-Kansas City's Healthcare Institute for Innovations in Quality and Saint Luke's Mid America Heart Institute, Kansas City.

出版信息

JAMA Netw Open. 2024 Feb 5;7(2):e2356693. doi: 10.1001/jamanetworkopen.2023.56693.

Abstract

IMPORTANCE

A primary objective in managing atrial fibrillation (AF) is to optimize patients' health status, which can be done only if physicians accurately quantify the outcomes associated with AF in patients' lives.

OBJECTIVE

To explore physicians' estimation of the health status of patients with AF and its association with subsequent care and outcomes.

DESIGN, SETTING, AND PARTICIPANTS: A multicenter, prospective cohort study was conducted in 2 outpatient practices in Tokyo, Japan. Participants included patients with newly diagnosed AF or those referred for initial treatment of AF at outpatient practices and treating physicians from November 8, 2018, to April 1, 2020. Data analysis was performed from December 22, 2022, to July 7, 2023.

EXPOSURES

Participating patients completed the Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaire, a 20-item tool covering 4 domains with a 7-point Likert scale; 3 domains (symptoms, daily activities, and treatment concerns) were used in this study. Blinded to patients' responses, treating physicians answered a 3-item questionnaire quantifying each patient's AFEQT domain with a single item. Patients' mean Likert scale responses within each AFEQT domain were subtracted from the physicians' assessments so that higher scores (≥0.5 points) indicate physician underestimation, while lower scores (≤0.5 points) indicate physician overestimation of the health status of patients with AF.

MAIN OUTCOMES AND MEASURES

The independent association of physician-patient concordance with treatment escalation (alteration or initiation of antiarrhythmic drugs, cardioversion, or catheter ablation) and 1-year adjusted changes in AFEQT scores.

RESULTS

Among 330 patients (238 [72.1%] men; mean [SD] age, 67.9 [11.9] years; 163 [49.4%] with paroxysmal AF), physicians correctly estimated health status in 112 patients (33.9%), underestimated it in 42 patients (12.7%), and overestimated it in 176 patients (53.3%). Treatment escalation occurred in 63.6% of patients whose health status was correctly estimated, 47.6% of those whose health status was underestimated, and 66.3% of patients whose health status was overestimated. After multivariable adjustment, underestimation of health status was independently associated with less treatment escalation (adjusted odds ratio, 0.43; 95% CI, 0.20-0.90) and less frequent AFEQT overall summary score improvement at 1 year (underestimated, 2.5 [95% CI, -1.6 to 6.7] vs correctly and overestimated health status, 8.4 [95% CI, 7.0-9.9] points; P = .01).

CONCLUSIONS AND RELEVANCE

In this cohort study, physician underestimation of the health status of patients with AF was common and associated with less aggressive treatment and less health status improvement at 1 year.

摘要

重要性

管理心房颤动 (AF) 的主要目标是优化患者的健康状况,只有医生准确地量化了患者生活中与 AF 相关的结果,才能实现这一目标。

目的

探讨医生对 AF 患者健康状况的评估及其与后续护理和结局的关系。

设计、地点和参与者:这是一项在日本东京的 2 家门诊诊所进行的多中心前瞻性队列研究。参与者包括新诊断为 AF 或因 AF 初诊而转诊至门诊诊所的患者,以及来自这些诊所的治疗医生。研究于 2018 年 11 月 8 日至 2020 年 4 月 1 日进行,数据分析于 2022 年 12 月 22 日至 2023 年 7 月 7 日进行。

暴露因素

参与患者完成了心房颤动对生活质量的影响(AFEQT)问卷,这是一个包含 4 个领域的 20 项工具,采用 7 点李克特量表;本研究使用了 3 个领域(症状、日常活动和治疗关注)。医生在不了解患者回答的情况下,通过回答 3 个项目来量化每个患者的 AFEQT 领域,每个项目用一个项目表示。患者在每个 AFEQT 领域的平均李克特量表评分与医生的评估结果相减,因此,较高的分数(≥0.5 分)表示医生低估,而较低的分数(≤0.5 分)表示医生高估 AF 患者的健康状况。

主要结果和测量指标

医生与患者一致性与治疗升级(改变或开始抗心律失常药物、电复律或导管消融)以及 AFEQT 评分在 1 年内的调整变化的独立关联。

结果

在 330 名患者(238 名男性[72.1%];平均[标准差]年龄 67.9[11.9]岁;163 名[49.4%]为阵发性 AF)中,112 名患者(33.9%)的健康状况被医生正确评估,42 名患者(12.7%)被低估,176 名患者(53.3%)被高估。正确评估健康状况的患者中有 63.6%接受了治疗升级,而低估健康状况的患者中有 47.6%接受了治疗升级,而高估健康状况的患者中有 66.3%接受了治疗升级。多变量调整后,健康状况被低估与治疗升级较少(调整后的优势比,0.43;95%CI,0.20-0.90)和 1 年时 AFEQT 总体综合评分改善较少相关(被低估,2.5[95%CI,-1.6 至 6.7]与正确和高估健康状况,8.4[95%CI,7.0-9.9]分;P=0.01)。

结论和相关性

在这项队列研究中,医生对 AF 患者健康状况的低估很常见,与治疗不积极和 1 年内健康状况改善较少有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f871/10891467/d376e51b7cc1/jamanetwopen-e2356693-g001.jpg

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