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利用基于各种纳米材料的化学传感器对 DMMP 模型模拟物进行感测有毒神经剂的最新进展。

Recent advances in sensing toxic nerve agents through DMMP model simulant using diverse nanomaterials-based chemical sensors.

机构信息

Department of Chemistry, Sri Venkateswara College (University of Delhi), Dhaula Kuan, New Delhi 110021, India; Department of Chemistry, Manipur University, Canchipur, Imphal 795003, Manipur, India; Polymer Research Laboratory, Department of Chemistry, Acharya Narendra Dev College (University of Delhi), Govindpuri, Kalkaji, New Delhi, 110019, India.

School of Chemical Sciences and Advanced Materials Research Center, Indian Institute of Technology Mandi, Kamand, Mandi 175075, Himachal Pradesh, India.

出版信息

Talanta. 2024 May 15;272:125785. doi: 10.1016/j.talanta.2024.125785. Epub 2024 Feb 22.

Abstract

Recent terrorist assaults have demonstrated the need for the exploration and design of sustainable and stable chemical sensors with quick reaction times combined with great sensitivity. Among several classes of chemical warfare agents, nerve agents have been proven to be the most hazardous. Even short-term exposure to them can result in severe toxic effects. Human beings inadvertently face the after-effects of these chemicals even several years after these chemicals were used. Due to the extreme toxicity and difficulty in handling, dimethyl methylphosphonate (DMMP), a simulant of nerve agents with much lesser toxicity, is frequently used in laboratories as a substitute. Having a chemical structure almost identical to those of nerve agents, DMMP can mimic the properties of nerve agents. Through this paper, authors have attempted to introduce the evolution of several chemical sensors used to detect DMMP in recent years, including field-effect transistors, chemicapacitors, chemiresistors, and mass-sensitive sensors. A detailed discussion of the role of nanomaterials as chemical sensors in the detection of DMMP has been the main focus of the work through a comprehensive overview of the research on gas sensors that have been reported making use of the properties of a wide range of nanomaterials.

摘要

近期的恐怖袭击事件表明,我们需要探索和设计具有快速响应时间和高灵敏度的可持续稳定化学传感器。在几类化学战剂中,神经毒剂已被证明是最危险的。即使短时间接触,也会导致严重的毒性作用。人类即使在这些化学物质使用多年后,仍会不经意间面临它们的后遗症。由于二甲基甲基膦酸酯(DMMP)的毒性要小得多,且处理起来极其困难,因此常被用作神经毒剂的模拟物,在实验室中被广泛使用。DMMP 的化学结构与神经毒剂几乎完全相同,因此可以模拟神经毒剂的性质。本文作者试图介绍近年来用于检测 DMMP 的几种化学传感器的发展,包括场效应晶体管、化学电容器、化学电阻器和质量敏感传感器。通过对利用各种纳米材料特性的气体传感器研究的全面综述,详细讨论了纳米材料作为化学传感器在 DMMP 检测中的作用。

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