Obbens E A, Leavens M E, Beal J W, Lee Y Y
Neurology. 1985 Sep;35(9):1274-8. doi: 10.1212/wnl.35.9.1274.
We reviewed records of 387 patients with cancer who had Ommaya reservoirs placed between October 1967 and December 1982. Complications of reservoir placement were reported in 27 patients, including intracranial hemorrhage (5 patients) and reservoir malfunction (15 patients). In 15 of 19 patients with meningitis, the infection was linked to the reservoir. The organism most frequently implicated was Staphylococcus epidermidis. Seizures, leukoencephalopathy, and pericatheter necrosis were seen in 10 patients who had received intraventricular chemotherapy.
我们回顾了1967年10月至1982年12月期间植入奥马亚贮液器的387例癌症患者的记录。27例患者报告了贮液器植入的并发症，包括颅内出血（5例）和贮液器故障（15例）。19例脑膜炎患者中有15例感染与贮液器有关。最常涉及的病原体是表皮葡萄球菌。10例接受脑室内化疗的患者出现了癫痫发作、白质脑病和导管周围坏死。
