Xu Qianyi, Vinogradskiy Yevgeniy, Grimm Jimm, Nie Wei, Dupre Pamela, Chawla Ashish K, Bajaj Gopal, Yang Haihua, LaCouture Tamara, Fan Jiajin
Department of Advanced Radiation Oncology and Proton Therapy, Inova Schar Cancer Institute, Fairfax, VA 22031, United States.
Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, United States.
Br J Radiol. 2024 Feb 28;97(1155):660-667. doi: 10.1093/bjr/tqae011.
To evaluate patient-specific quality assurance (PSQA) of 3 targets in a single delivery using a novel film-based phantom.
The phantom was designed to rotate freely as a sphere and could measure 3 targets with film in a single delivery. After identifying the coordinates of 3 targets in the skull, the rotation angles about the equator and meridian were computed for optimal phantom setup, ensuring the film plane intersected the 3 targets. The plans were delivered on the CyberKnife system using fiducial tracking. The irradiated films were scanned and processed. All films were analysed using 3 gamma criteria.
Fifteen CyberKnife test plans with 3 different modalities were delivered on the phantom. Both automatic and marker-based registration methods were applied when registering the irradiated film and dose plane. Gamma analysis was performed using a 3%/1 mm, 2%/1 mm, and 1%/1 mm criteria with a 10% threshold. For the automatic registration method, the passing rates were 98.2% ± 1.9%, 94.2% ± 3.7%, and 80.9% ± 6.3%, respectively. For the marker-based registration approach, the passing rates were 96.4% ± 2.7%, 91.7% ± 4.3%, and 78.4% ± 6.2%, respectively.
A novel spherical phantom was evaluated for the CyberKnife system and achieved acceptable PSQA passing rates using TG218 recommendations. The phantom can measure true-composite dose and offers high-resolution results for PSQA, making it a valuable device for robotic radiosurgery.
This is the first study on PSQA of 3 targets concurrently on the CyberKnife system.
使用一种新型的基于胶片的体模评估单次照射中3个靶点的患者特异性质量保证(PSQA)。
该体模设计为可像球体一样自由旋转,并且能够在单次照射中用胶片测量3个靶点。在确定颅骨中3个靶点的坐标后,计算围绕赤道和子午线的旋转角度以实现最佳体模设置,确保胶片平面与3个靶点相交。使用基准跟踪在射波刀系统上进行计划照射。对照射后的胶片进行扫描和处理。所有胶片均使用3种伽马标准进行分析。
在体模上实施了15个具有3种不同模式的射波刀测试计划。在对照射后的胶片和剂量平面进行配准时,同时应用了自动和基于标记的配准方法。使用具有10%阈值的3%/1毫米、2%/1毫米和1%/1毫米标准进行伽马分析。对于自动配准方法,通过率分别为98.2%±1.9%、94.2%±3.7%和80.9%±6.3%。对于基于标记的配准方法,通过率分别为96.4%±2.7%、91.7%±4.3%和78.4%±6.2%。
对射波刀系统的一种新型球形体模进行了评估,并根据TG218建议获得了可接受的PSQA通过率。该体模可以测量真实的复合剂量,并为PSQA提供高分辨率结果,使其成为机器人放射外科的一种有价值的设备。
这是第一项关于在射波刀系统上同时对3个靶点进行PSQA的研究。