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《儿童轮状病毒胃肠炎免疫预防专家共识(2024年版)》

[Expert consensus on immunoprophylaxis of childhood rotavirus gastroenteritis (2024 version)].

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2024 Feb 23;58:1-33. doi: 10.3760/cma.j.cn112150-20231220-00472.

Abstract

Rotavirus gastroenteritis (RVGE) is a global public health challenge that seriously threatens the health of children under 5 years of age. In China, the burden associated with RVGE is substantial and its prevention and control are difficult. On the basis of and , in this updated consensus we systematically review advances in RVGE epidemiological research; safety, effectiveness/efficacy, and immune persistence of post-marketing rotavirus (RV) vaccines; and RV immunization strategies. We also provide guidance for RVGE diagnosis and treatment. Following the principles of prioritizing prevention and integrating medical and preventive approaches, we aim to facilitate the implementation of comprehensive prevention and control measures focusing on RV vaccination to reduce the childhood RVGE disease burden and provide reference for professionals working for disease control and prevention, vaccination, clinical diagnosis and treatment, and related fields.

摘要

轮状病毒胃肠炎(RVGE)是一项全球性公共卫生挑战,严重威胁5岁以下儿童的健康。在中国,RVGE相关负担沉重,其预防和控制颇具难度。基于[相关内容1]和[相关内容2],在本更新共识中,我们系统回顾了RVGE流行病学研究进展;上市后轮状病毒(RV)疫苗的安全性、有效性/效力及免疫持久性;以及RV免疫策略。我们还为RVGE的诊断和治疗提供指导。遵循预防为主、防治结合的原则,我们旨在推动以RV疫苗接种为重点的综合防控措施的实施,以减轻儿童RVGE疾病负担,并为疾病防控、疫苗接种、临床诊断治疗及相关领域的专业人员提供参考。

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