Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, Beijing, China.
School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Front Public Health. 2024 Aug 8;12:1423573. doi: 10.3389/fpubh.2024.1423573. eCollection 2024.
Rotavirus is globally recognized as an important cause of acute gastroenteritis in young children. Whereas previous studies focused more on sporadic diarrhea, the epidemiological characteristics of rotavirus outbreaks have not been systematically understood.
This systematic review was carried out according to the Preferred Reporting Items for Systematic Review and Meta-Analysis standards, WANFANG, China National Knowledge Infrastructure (CNKI), PubMed, and Web of Science databases were searched from database inception to February 20, 2022. We used SPSS 21.0 statistical software for data analysis, RStudio1.4.1717, and ArcGIS trial version for plotting bar graphs and maps.
Among 1,596 articles, 78 were included, with 92 rotavirus outbreaks and 96,128 cases. Most outbreaks (67.39%, 62/92) occurred in winter and spring. The number of rotavirus outbreaks reported in the eastern region was more than that in the western region. Outbreaks were most commonly reported in villages (33/92, 35.87%), followed by hospitals (19, 20.65%). The outbreak duration was longer in factories and workers' living places, and villages, while it was shorter in hospitals. Waterborne transmission was the main transmission mode, with the longest duration and the largest number of cases. Rotavirus groups were identified in 66 outbreaks, with 40 outbreaks (60.61%) caused by Group B rotaviruses and 26 outbreaks (39.39%) caused by Group A rotaviruses. Significant differences were found in duration, number of cases, settings, population distribution, and transmission modes between Groups A and B rotavirus outbreaks.
Rotavirus is an important cause of acute gastroenteritis outbreaks in China. It should also be considered in the investigation of acute gastroenteritis outbreaks, especially norovirus-negative outbreaks.
轮状病毒被全球公认为导致婴幼儿急性胃肠炎的重要原因。虽然以前的研究更多地关注散发性腹泻，但轮状病毒暴发的流行病学特征尚未得到系统了解。
本系统评价按照系统评价和荟萃分析的首选报告项目进行，从数据库创建到 2022 年 2 月 20 日，检索了万方、中国知网（CNKI）、PubMed 和 Web of Science 数据库。使用 SPSS 21.0 统计软件进行数据分析，RStudio1.4.1717 和 ArcGIS 试用版绘制条形图和地图。
在 1596 篇文章中，有 78 篇被纳入，其中包括 92 起轮状病毒暴发和 96128 例病例。大多数暴发（67.39%，62/92）发生在冬春季节。东部地区报告的轮状病毒暴发数量多于西部地区。暴发最常发生在村庄（33/92，35.87%），其次是医院（19，20.65%）。工厂和工人居住地以及村庄的暴发持续时间较长，而医院的暴发持续时间较短。水源传播是主要的传播方式，持续时间最长，病例数最多。在 66 次暴发中鉴定出轮状病毒群，其中 B 群轮状病毒引起 40 次暴发（60.61%），A 群轮状病毒引起 26 次暴发（39.39%）。A 群和 B 群轮状病毒暴发在持续时间、病例数、发生地点、人群分布和传播方式上存在显著差异。
轮状病毒是中国急性胃肠炎暴发的重要原因。在调查急性胃肠炎暴发时，特别是诺如病毒阴性暴发时，也应考虑轮状病毒。
