Su Wei, Wang Xin-Yue, Fu Gang, Chen Wu-Xian, Shen Xiang-Ru, Li Bin, Wang Wei
School of Pharmacy, Hunan University of Chinese Medicine Changsha 410208, China Traditional Chinese Medicine and Ethnomedicine Innovation & Development International Laboratory, Hunan University of Chinese Medicine Changsha 410208, China Department of Periodical Press, Hunan University of Chinese Medicine Changsha 410208, China.
School of Pharmacy, Hunan University of Chinese Medicine Changsha 410208, China.
Zhongguo Zhong Yao Za Zhi. 2024 Jan;49(1):26-38. doi: 10.19540/j.cnki.cjcmm.20230718.201.
The 29 plant species in the Kadsura genus of the Schisandraceae family are mainly distributed in eastern and southeas-tern Asia. Ten species of plants in this genus are distributed in China, some of which are folk medicinal plants with activating blood circulation, relieving pain, dispelling wind, and dehumidifying effects. Their main constituents are lignans and triterpenes. The current pharmacology and clinical studies have shown that their extracts and constituents have anti-rheumatoid arthritis, liver protection, antioxidation, anti-inflammatory, and other biological activities. The rheumatologic and liver diseases can also be treated with the plants in the clinic. The new chemical constituents reported in the last decade(2012 to date) from the plants of Kadsura genus in China, as well as their pharmacological effects and clinical applications in recent years were reviewed, so as to provide a theoretical basis for further research on the genus.
五味子科南五味子属的29种植物主要分布于东亚和东南亚地区。该属植物在中国有10种,其中一些为民间药用植物,具有活血化瘀、祛风除湿的功效。其主要成分为木脂素和三萜类化合物。目前的药理学和临床研究表明,它们的提取物和成分具有抗类风湿性关节炎、保肝、抗氧化、抗炎等生物活性。临床上也可用这些植物治疗风湿性疾病和肝脏疾病。本文综述了近十年来(2012年至今)中国南五味子属植物报道的新化学成分及其近年来的药理作用和临床应用,为该属植物的进一步研究提供理论依据。