Kobayashi Yuya, Kasuga Kazuki, Shimizu Yusaku, Sekijima Yoshiki
Department of Neurology, Ina Central Hospital, Japan.
Department of Medicine (Neurology & Rheumatology), Shinshu University School of Medicine, Japan.
Intern Med. 2024 Oct 1;63(19):2695-2697. doi: 10.2169/internalmedicine.3094-23. Epub 2024 Feb 26.
We report the case of an 80-year-old man with Frey syndrome that developed 30 years postoperatively, which is an exceptionally long period before its occurrence. Sweating and flushing occurred on only the side of his face where the surgery was performed, and he had no other causative abnormalities. Following treatment with botulinum toxin, the patient's symptoms resolved. Extremely early- and late-onset cases do not fit the conventional paradigm of this pathology. Various surgical methods to prevent this syndrome have been explored, but complete prevention has not yet been achieved. These findings suggest that the underlying pathophysiology of Frey syndrome may be more complex than previously recognized.
我们报告了一例80岁男性患者，其在术后30年出现了 Frey 综合征，这是该综合征发生前极为漫长的一段时间。出汗和面部潮红仅出现在手术一侧的脸部，且他没有其他导致该症状的异常情况。经肉毒杆菌毒素治疗后，患者症状得以缓解。极早期和极晚期发病的病例并不符合这种病理状况的传统模式。人们已经探索了多种预防该综合征的手术方法，但尚未实现完全预防。这些发现表明，Frey 综合征的潜在病理生理学可能比之前认为的更为复杂。
