Insilico Medicine Canada Inc., 3710-1250 René-Lévesque Blvd. W, Montreal, Quebec, Canada H3B 4W8.
Insilico Medicine Hong Kong Limited, Hong Kong Science and Technology Park, Hong Kong.
J Chem Inf Model. 2024 May 27;64(10):3961-3969. doi: 10.1021/acs.jcim.3c01619. Epub 2024 Feb 25.
PandaOmics is a cloud-based software platform that applies artificial intelligence and bioinformatics techniques to multimodal omics and biomedical text data for therapeutic target and biomarker discovery. PandaOmics generates novel and repurposed therapeutic target and biomarker hypotheses with the desired properties and is available through licensing or collaboration. Targets and biomarkers generated by the platform were previously validated in both and studies. PandaOmics is a core component of Insilico Medicine's Pharma.ai drug discovery suite, which also includes Chemistry42 for the generation of novel small molecules, and inClinico─a data-driven multimodal platform that forecasts a clinical trial's probability of successful transition from phase 2 to phase 3. In this paper, we demonstrate how the PandaOmics platform can efficiently identify novel molecular targets and biomarkers for various diseases.
熊猫分析是一个基于云的软件平台,它将人工智能和生物信息学技术应用于多模态组学和生物医学文本数据,用于治疗靶点和生物标志物的发现。熊猫分析生成具有所需特性的新颖和再利用的治疗靶点和生物标志物假设,并通过许可或许可合作获得。该平台生成的靶点和生物标志物在 和 研究中得到了验证。熊猫分析是 Insilico Medicine 的 Pharma.ai 药物发现套件的核心组成部分,该套件还包括 Chemistry42 用于新型小分子的生成,以及 inClinico——一个数据驱动的多模态平台,可预测临床试验从第 2 阶段到第 3 阶段成功过渡的概率。在本文中,我们展示了熊猫分析平台如何有效地识别各种疾病的新型分子靶点和生物标志物。