Shi Leyao, Feng Yahui, Shi Dongmei
The Second Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People's Republic of China.
The Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, Shandong, People's Republic of China.
Infect Drug Resist. 2024 Feb 19;17:665-672. doi: 10.2147/IDR.S438079. eCollection 2024.
The clinical manifestation of superficial candidiasis varies depending on the infectious sites and causative species that brings a great challenge to diagnose or treat without mycological or pathological evidence in clinical settings. Oral mucosal candidiasis and onychomycosis are most common types of superficial candidiasis. Typically, oral mucosal candidiasis manifests as white or erythematous thrush coated on the tongue and other interior oral cavity; and onychomycosis caused by spp. presents with thick, fragile, or cracked fingernails or toenails in yellow or white discoloration. Here, we report one case of patient with a black hairy tongue caused by and one case of greenish discolored onychomycosis caused by . The cases of superficial candidiasis with the same discolored lesions were searched in literature and compared with our cases in clinical manifestation, causative pathogen and treatment. These cases highlight the importance of mycological diagnosis for identifying non- species (NCAC) in superficial infections to guide an effective therapy.
浅表念珠菌病的临床表现因感染部位和致病菌种而异,在临床环境中,若无真菌学或病理学证据,诊断或治疗将面临巨大挑战。口腔黏膜念珠菌病和甲癣是浅表念珠菌病最常见的类型。通常,口腔黏膜念珠菌病表现为舌部及口腔其他内部区域覆盖的白色或红斑型鹅口疮;由某些菌种引起的甲癣表现为指甲或趾甲增厚、脆弱或开裂,呈黄色或白色变色。在此,我们报告1例由某菌种引起的黑毛舌患者及1例由另一菌种引起的绿色变色甲癣患者。在文献中检索了具有相同变色病变的浅表念珠菌病病例,并与我们病例的临床表现、致病病原体及治疗进行比较。这些病例突出了真菌学诊断在识别浅表感染中的非白色念珠菌(NCAC)以指导有效治疗方面的重要性。