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肝中叶切除术在儿童肝脏中央型肿瘤中的作用

Role of Mesohepatectomy for Pediatric Centrally Located Liver Tumors.

作者信息

Nirmalan Shajini, Ramaswamy Senthilnathan, Shanmugam Vivek, Natarajan Karpaga Vinayagam

机构信息

Department of Paediatric Surgery, Institute of Child Health, Madras Medical College, Chennai, Tamil Nadu, India.

出版信息

J Indian Assoc Pediatr Surg. 2024 Jan-Feb;29(1):51-55. doi: 10.4103/jiaps.jiaps_190_23. Epub 2024 Jan 12.

Abstract

BACKGROUND

Mesohepatectomy (MH) or central hepatectomy (CH) is a recognized surgical technique for centrally located pediatric liver tumors. This technique of liver resection avoids extended liver resections and thereby helps in the preservation of liver parenchyma. In this article, we aim to analyze our experience and outcome with this technique of liver resection.

METHODS

A retrospective analysis of patients who underwent MH from January 2015 to June 2023 at our institute was performed. The variables analyzed include demographics, preoperative treatment, perioperative management, and postoperative outcome.

RESULTS

A total of five patients underwent CH. Four patients had hepatoblastoma, and one patient had mesenchymal hamartoma. All four patients with hepatoblastoma received neoadjuvant chemotherapy. All five patients had negative surgical margins, and one of the five developed disease recurrences necessitating resurgery and ultimately died of metastasis. one patient sustained intraoperative major bile duct injuries, and one patient had postoperative Abnormal, well-circumscribed, extra-biliary collection of bile.

CONCLUSION

MH with clear margins is feasible in the selected subset of pediatric liver tumors involving segments IV, V, and VIII with outcomes equivalent to extended hepatic resections.

摘要

背景

肝中叶切除术(MH)或中央肝切除术(CH)是一种公认的用于治疗位于肝脏中央的小儿肝脏肿瘤的手术技术。这种肝切除技术避免了广泛的肝切除,从而有助于保留肝实质。在本文中,我们旨在分析我们使用这种肝切除技术的经验和结果。

方法

对2015年1月至2023年6月在我院接受MH的患者进行回顾性分析。分析的变量包括人口统计学、术前治疗、围手术期管理和术后结果。

结果

共有5例患者接受了CH。4例患者患有肝母细胞瘤,1例患者患有间叶性错构瘤。所有4例肝母细胞瘤患者均接受了新辅助化疗。所有5例患者手术切缘均为阴性,其中1例出现疾病复发,需要再次手术,最终死于转移。1例患者术中发生主要胆管损伤,1例患者术后出现异常的、边界清晰的肝外胆汁积聚。

结论

在选定的累及IV、V和VIII段的小儿肝脏肿瘤亚组中,切缘清晰的MH是可行的,其结果与广泛肝切除相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8af/10883162/3b6606d535f8/JIAPS-29-51-g001.jpg

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