Pickardt C R
Langenbecks Arch Chir. 1985;366:45-9. doi: 10.1007/BF01836604.
The risk of recurrent hyperthyroidism can be eliminated indefinitely in patients with autonomously functioning thyroid tissue (AFTT) by selective surgery or radioiodine, whereas medical treatment inhibits only the actual thyroid hormone over-production. Therefore, AFTT should be removed. In immunogenic hyperthyroidism the natural history of the disease can be influenced only symptomatically. The relapse rate after medical treatment is more than 50%. After surgical or radioactive therapy long-term remission of hyperthyroidism, not of the underlying thyroid disease can be achieved more effectively. Therefore surgical treatment should be preferred.
对于具有自主功能性甲状腺组织(AFTT)的患者,通过选择性手术或放射性碘治疗可无限期消除甲亢复发风险,而药物治疗仅能抑制实际的甲状腺激素过度分泌。因此,应切除AFTT。在免疫性甲亢中,疾病的自然病程仅能在症状方面受到影响。药物治疗后的复发率超过50%。手术或放射治疗后,可更有效地实现甲亢的长期缓解,而非潜在甲状腺疾病的长期缓解。因此,应首选手术治疗。