成釉细胞瘤转变为成釉细胞癌的罕见病例——1例报告
A Rare Condition of Ameloblastoma Transforming into Ameloblastomic Carcinoma - A Case Report.
作者信息
Somabhatta Manojnya, Ananthnag Jakkula, Damera Srikanth, Pamidi V R Chandrababu, Gogineni Tarun, Burugupalli Sriram
机构信息
Department of Oral and Maxillofacial Surgery, GSL Dental College and Hospital, Rajahmundry, Andhra Pradesh, India.
GSL Cancer Trust, Rajahmundry, Andhra Pradesh, India.
出版信息
Ann Maxillofac Surg. 2023 Jul-Dec;13(2):244-247. doi: 10.4103/ams.ams_66_23. Epub 2023 Nov 24.
RATIONALE
Ameloblastic carcinoma is defined as an ameloblastoma in which there is histological evidence of malignancy in primary tumour or recurrent tumour regardless if it has metastasised or not. It is aggressive in nature.
PATIENT CONCERNS
The patient presented with a painful swelling associated with restricted mouth opening.
DIAGNOSIS
This is the clinical profile of a patient who has presented with a recurrent ameloblastic carcinoma.
TREATMENT
Histological features of the excised specimen resemble ameloblastic carcinoma constituting cytological atypia with tall columnar cells.
OUTCOME
Excision of tumour was done. Reconstruction was done using pectoralis major myocutaneous flap.
TAKE-AWAY LESSONS: Ameloblastic carcinoma is an aggressive tumour and constitutes destruction and distant metastatic spread. Hence, aggressive resection is the choice of treatment along with a long-term follow-up for better quality of life.
理论依据
成釉细胞癌被定义为一种成釉细胞瘤，其原发肿瘤或复发肿瘤具有组织学上的恶性证据，无论是否发生转移。它本质上具有侵袭性。
患者情况
患者出现疼痛性肿胀并伴有张口受限。
诊断
这是一名复发性成釉细胞癌患者的临床特征。
治疗
切除标本的组织学特征类似于成釉细胞癌，表现为具有高柱状细胞的细胞学异型性。
结果
进行了肿瘤切除。采用胸大肌肌皮瓣进行重建。
经验教训
成釉细胞癌是一种侵袭性肿瘤，可导致破坏和远处转移扩散。因此，积极切除是治疗的选择，并需长期随访以提高生活质量。
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