Kekovic Vladan, Schicho Kurt, Perisanidis Christos, Mikovic Nikola, Stanimirovic Dragan, Soldatovic Ivan, Sinobad Vladimir
Department of Maxillofacial Surgery, Faculty of Dentistry, University of Belgrade, Belgrade, Serbia.
Department of Cranio-Maxillofacial Surgery, AKH University Hospital, Vienna, Austria.
Ann Maxillofac Surg. 2023 Jul-Dec;13(2):200-204. doi: 10.4103/ams.ams_105_23. Epub 2023 Dec 18.
Osteomyelitis of the jaws is a common disease of the maxillofacial region. The goal of treatment is to alleviate pain, reduce infection, inhibit the progression of the disease and induce bone and mucosal healing. In addition to surgical management and antibiotic and oxygen hyperbaric therapy, new therapeutic strategies for the treatment of osteomyelitis are developed. One of the novel approaches is photobiomodulation therapy or low-level light therapy (LLLT).
After surgical treatment, experimental group patients ( = 4) were treated with LLLT for five sessions with an extraoral pulsed 635-nm LED lamp (Repuls7, Repuls Lichtmedizintechnik GmbH, Austria), maximum output power: 140 mW/cm, frequency: 2.5 Hz, duty cycle: 50%. Clinical achievement and patient pain perception (through Visual Analogue Scale score) were evaluated at 1-, 3- and 6-month follow-up appointments and compared with control group ( = 4) patients, treated with standard therapy.
At three and six months, clinical achievement was better in patients treated with LLLT. Pain and discomfort resolution was significantly greater in the experimental group.
Taking into consideration the results of this study, it can be concluded that LLLT shows potential for improving clinical outcome of surgical and medical treatment of secondary chronic osteomyelitis of the jaws. Furthermore, pain and discomfort were significantly reduced in patients treated with LLLT. Further research with a larger sample size is needed to obtain a more accurate insight into this promising field.
颌骨骨髓炎是颌面区域的一种常见疾病。治疗的目标是减轻疼痛、减少感染、抑制疾病进展并促进骨和黏膜愈合。除了手术治疗、抗生素和高压氧治疗外,还开发了治疗骨髓炎的新治疗策略。其中一种新方法是光生物调节疗法或低强度光疗法(LLLT)。
手术治疗后,实验组患者(n = 4)使用外置脉冲635纳米发光二极管灯(Repuls7,Repuls Lichtmedizintechnik GmbH,奥地利)进行5次LLLT治疗,最大输出功率:140毫瓦/平方厘米,频率:2.5赫兹,占空比:50%。在1个月、3个月和6个月的随访预约中评估临床疗效和患者疼痛感知(通过视觉模拟量表评分),并与接受标准治疗的对照组患者(n = 4)进行比较。
在3个月和6个月时,接受LLLT治疗的患者临床疗效更好。实验组疼痛和不适的缓解明显更大。
考虑到本研究的结果,可以得出结论,LLLT显示出改善颌骨继发性慢性骨髓炎手术和药物治疗临床结果的潜力。此外,接受LLLT治疗的患者疼痛和不适明显减轻。需要进行更大样本量的进一步研究,以更准确地了解这个有前景的领域。