Kashyap Ashutosh, Pokhrel Biraj, Bhatta Aaraju, Aryal Savita, Khanal Shambhu
Department of Internal Medicine, Tribhuvan University Institute of Medicine, Kathmandu, NPL.
Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, NPL.
Cureus. 2024 Jan 24;16(1):e52845. doi: 10.7759/cureus.52845. eCollection 2024 Jan.
Rheumatoid arthritis (RA) is a chronic inflammatory disease, with rheumatoid vasculitis (RV) being its most threatening complication. We report a case of a 70-year-old female presenting with gangrene of the tips of fingers and toes early in the course of RA, which is a rare manifestation. The skin is the most commonly affected organ in RV, followed by the peripheral nerves. However, almost every organ system can get implicated. The management of RV is mostly empirical, with high-dose glucocorticoids and cyclophosphamide. Early diagnosis and optimum management are essential in preventing severe complications of the disease.
类风湿关节炎（RA）是一种慢性炎症性疾病，类风湿血管炎（RV）是其最具威胁性的并发症。我们报告一例70岁女性，在类风湿关节炎病程早期出现手指和脚趾末端坏疽，这是一种罕见的表现。皮肤是类风湿血管炎最常受累的器官，其次是周围神经。然而，几乎每个器官系统都可能受到影响。类风湿血管炎的治疗大多基于经验，采用大剂量糖皮质激素和环磷酰胺。早期诊断和最佳治疗对于预防该疾病的严重并发症至关重要。
