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卢西奥现象:一例罕见的皮肤坏死病例。

Lucio Phenomenon: An Unusual Case of Skin Necrosis.

作者信息

Rusia Kaveri, Saoji Vikrant, Madke Bhushan, Singh Adarshlata

机构信息

Department of Dermatology, Venereology and Leprosy, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, Wardha, India.

出版信息

Case Rep Dermatol. 2024 Feb 23;16(1):47-54. doi: 10.1159/000536370. eCollection 2024 Jan-Dec.

DOI:10.1159/000536370
PMID:38406643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10890809/
Abstract

INTRODUCTION

Lucio leprosy is a non-nodular diffuse type of lepromatous leprosy first described by Lucio and Alvarado. Lucio phenomenon is a rare vasculonecrotic reaction characterized by cutaneous necrosis with minimal constitutional features.

CASE PRESENTATION

We describe an unusual case of a 53-year-old man from Central India who had blisters, ulcers, and widespread erosions on his foot, forearms, and arms. The diagnosis of lepromatous leprosy with the Lucio phenomenon was established after thorough evaluation by clinical findings, histopathological findings, and slit-skin smear examination.

CONCLUSION

Lucio phenomenon is an uncommon cause of cutaneous infarction and necrosis. Primary care physicians should keep a high index of suspicion in patients with cutaneous necrosis and minimal constitution features. Since leprosy is a relatively curable disease, primary care physicians should think of a rare form of lepromatous leprosy presenting with cutaneous necrosis, especially in non-endemic zones.

摘要

引言

卢西奥麻风是一种非结节性弥漫型瘤型麻风,最初由卢西奥和阿尔瓦拉多描述。卢西奥现象是一种罕见的血管坏死反应,其特征为皮肤坏死且全身症状轻微。

病例报告

我们描述了一例来自印度中部的53岁男性的罕见病例,其足部、前臂和手臂出现水疱、溃疡及广泛糜烂。通过临床表现、组织病理学检查结果及皮肤涂片检查进行全面评估后,确诊为伴有卢西奥现象的瘤型麻风。

结论

卢西奥现象是皮肤梗死和坏死的罕见原因。基层医疗医生应对有皮肤坏死且全身症状轻微的患者保持高度怀疑。由于麻风是一种相对可治愈的疾病,基层医疗医生应考虑到一种罕见的以皮肤坏死为表现的瘤型麻风,尤其是在非流行地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/448b6503ba6e/cde-2024-0016-0001-536370_F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/1a0f552228a2/cde-2024-0016-0001-536370_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/7b37d2afa4dd/cde-2024-0016-0001-536370_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/ee3279dd7215/cde-2024-0016-0001-536370_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/448b6503ba6e/cde-2024-0016-0001-536370_F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/1a0f552228a2/cde-2024-0016-0001-536370_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/7b37d2afa4dd/cde-2024-0016-0001-536370_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/ee3279dd7215/cde-2024-0016-0001-536370_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81e1/10890809/448b6503ba6e/cde-2024-0016-0001-536370_F04.jpg

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本文引用的文献

1
Lucio's phenomenon.卢西奥现象
J Microbiol Immunol Infect. 2023 Jun;56(3):647-648. doi: 10.1016/j.jmii.2022.12.010. Epub 2022 Dec 30.
2
COVID-19: A new cause of cutaneous microvascular occlusion syndrome.新型冠状病毒肺炎:皮肤微血管闭塞综合征的新病因
J Res Med Sci. 2021 Nov 29;26:119. doi: 10.4103/jrms.jrms_560_21. eCollection 2021.
3
Lucio's phenomenon: A systematic literature review of definition, clinical features, histopathogenesis and management.卢西奥现象:定义、临床特征、组织病理学发病机制和治疗的系统文献综述。
Indian J Dermatol Venereol Leprol. 2022 May-Jun;88(4):464-477. doi: 10.25259/IJDVL_909_19.
4
A case report of rhino-facial mucormycosis in a non-diabetic patient with COVID-19: a systematic review of literature and current update.非糖尿病合并 COVID-19 患者的鼻面部毛霉菌病病例报告:文献系统评价及最新进展
BMC Infect Dis. 2021 Sep 3;21(1):906. doi: 10.1186/s12879-021-06625-3.
5
Lucio's Phenomenon.卢西奥现象
N Engl J Med. 2021 Apr 29;384(17):1646. doi: 10.1056/NEJMicm2025081.
6
Epidemiology and Diagnosis of Mucormycosis: An Update.毛霉病的流行病学与诊断:最新进展
J Fungi (Basel). 2020 Nov 2;6(4):265. doi: 10.3390/jof6040265.
7
Lucio Phenomenon: A Rare Presentation of Hansen's Disease.卢西奥现象:麻风病的一种罕见表现。
J Clin Aesthet Dermatol. 2019 Dec;12(12):35-38. Epub 2019 Dec 1.
8
Pigmented purpura and cutaneous vascular occlusion syndromes.色素性紫癜性及皮肤血管闭塞综合征
An Bras Dermatol. 2018 Jun;93(3):397-404. doi: 10.1590/abd1806-4841.20187459.
9
Lucio phenomenon in non-endemic area of Northeast Asia.东北亚非流行地区的卢西奥现象。
J Eur Acad Dermatol Venereol. 2017 Apr;31(4):e192-e194. doi: 10.1111/jdv.13920. Epub 2016 Aug 31.
10
Leprosy: review of the epidemiological, clinical, and etiopathogenic aspects - part 1.麻风病:流行病学、临床及病因学方面综述 - 第1部分
An Bras Dermatol. 2014 Mar-Apr;89(2):205-18. doi: 10.1590/abd1806-4841.20142450.