Edward Via College of Osteopathic Medicine, Monroe, LA, USA.
Department of Internal Medicine, Englewood Health/Hackensack University, Englewood, NJ, USA.
J Ayub Med Coll Abbottabad. 2023 Oct-Dec;35(4):675-679. doi: 10.55519/JAMC-04-12307.
Takotsubo syndrome (TTS), Takotsubo cardiomyopathy, or stress-induced cardiomyopathy are interchangeable terms characterized by transient left ventricular systolic dysfunction, electrocardiographic changes, and cardiac biomarker elevation similar to acute coronary syndrome (ACS), without the presence of obstructive epicardial coronary artery disease. It predominantly affects postmenopausal females and manifests in the presence of stressful triggers such as severe physical or emotional stress, natural disasters, unexpected death of relatives, acute medical illnesses, etc. TTS was initially considered to be a benign condition however recent studies have shown that it may be associated with complications and mortality similar to ACS. Rare reports of TTS triggered by diabetic ketoacidosis (DKA) have been published. Herein we describe a case of an elderly female with a history of type II diabetes mellitus (DM) who was admitted with DKA and subsequently developed TTS that resolved after treatment of DKA and implementation of heart failure therapies.
心尖球囊综合征（TTS）、心尖球形心肌病或应激性心肌病是可互换的术语，其特征为短暂性左心室收缩功能障碍、心电图变化和类似急性冠状动脉综合征（ACS）的心脏生物标志物升高，但不存在阻塞性心外膜冠状动脉疾病。它主要影响绝经后女性，在应激诱因存在的情况下发生，如剧烈的身体或情绪压力、自然灾害、亲属意外死亡、急性内科疾病等。TTS 最初被认为是一种良性疾病，但最近的研究表明，它可能与 ACS 相似，与并发症和死亡率相关。已经发表了一些关于糖尿病酮症酸中毒（DKA）引发 TTS 的罕见报道。在此，我们描述了一例患有 2 型糖尿病（DM）病史的老年女性，因 DKA 入院，随后发展为 TTS，在 DKA 治疗和心力衰竭治疗后 TTS 得到缓解。
