Düchting W, Vogelsaenger T
Biosystems. 1985;18(1):79-91. doi: 10.1016/0303-2647(85)90061-9.
This paper illustrates how to apply methods of systems analysis, control theory and simulation to the field of biology and medicine. For this purpose normal and abnormal cell growth has been modelled at different levels. It was possible to simulate three-dimensional tumor growth and different kinds of treatment. The paper shows how tumor treatment may be optimized in the long run using computer simulation experiments as a powerful new tool prior to clinical therapy.
本文阐述了如何将系统分析、控制理论和模拟方法应用于生物学和医学领域。为此，已在不同层面上对正常和异常细胞生长进行了建模。能够模拟三维肿瘤生长及不同类型的治疗。本文展示了在临床治疗之前，如何利用计算机模拟实验这一强大的新工具从长远角度优化肿瘤治疗。
