Recent progress in modelling and simulation of three-dimensional tumor growth and treatment.

This paper illustrates how to apply methods of systems analysis, control theory and simulation to the field of biology and medicine. For this purpose normal and abnormal cell growth has been modelled at different levels. It was possible to simulate three-dimensional tumor growth and different kinds of treatment. The paper shows how tumor treatment may be optimized in the long run using computer simulation experiments as a powerful new tool prior to clinical therapy.