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隆突性皮肤纤维肉瘤:一项临床病理及免疫组化研究并文献复习

Dermatofibrosarcoma protuberans: a clinicopathological and immunohistochemical study with a review of the literature.

作者信息

Fletcher C D, Evans B J, MacArtney J C, Smith N, Wilson Jones E, McKee P H

出版信息

Histopathology. 1985 Sep;9(9):921-38. doi: 10.1111/j.1365-2559.1985.tb02878.x.

Abstract

Forty-one cases of dermatofibrosarcoma protuberans are presented. The clinical features and histopathological appearances are described. Immunohistochemical staining of thirteen cases with antisera to lysozyme, alpha 1-antichymotrypsin and S-100 protein has provided no evidence to support either a histiocytic or neuroectodermal origin for these tumours. In reviewing the literature, the histogenetic origin, differential diagnosis and malignant potential of dermatofibrosarcoma protuberans are discussed.

摘要

本文报告了41例隆突性皮肤纤维肉瘤。描述了其临床特征和组织病理学表现。用抗溶菌酶、α1-抗胰凝乳蛋白酶和S-100蛋白的抗血清对13例病例进行免疫组织化学染色,未发现证据支持这些肿瘤起源于组织细胞或神经外胚层。在回顾文献时,讨论了隆突性皮肤纤维肉瘤的组织发生学起源、鉴别诊断和恶性潜能。

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