Angelos S A, Meyers J A
J Forensic Sci. 1985 Oct;30(4):1022-47.
Abuse of the hypnotic quinazolinone is well recognized and increasing. Clandestine laboratories producing methaqualone (2-methyl-3-ortho-tolyl-4(3H) quinazolinone) and mecloqualone (2-methyl-3-ortho-chlorophenyl-4(3H) quinazolinone) have been discovered throughout the United States. These laboratories utilize one of many synthesis routes to produce the illicit quinazolinone. Frequently, the clandestine chemist has little, if any, formal education in chemistry; does not keep notes; and does not label flasks and beakers containing solutions. The forensic chemist may be asked to analyze unmarked reaction mixtures that were seized in a clandestine laboratory raid. As a result, a rapid method of isolation and identification of the precursors and products of such a mixture is presented.
对催眠性喹唑啉酮的滥用已广为人知且呈上升趋势。在美国各地已发现了生产甲喹酮（2-甲基-3-邻甲苯基-4(3H)喹唑啉酮）和甲氯喹酮（2-甲基-3-邻氯苯基-4(3H)喹唑啉酮）的秘密实验室。这些实验室利用多种合成路线之一来生产非法喹唑啉酮。通常，秘密化学家几乎没有（如果有的话）化学方面的正规教育；不做笔记；也不标记装有溶液的烧瓶和烧杯。法医化学家可能会被要求分析在秘密实验室突袭中查获的未标记反应混合物。因此，本文提出了一种快速分离和鉴定此类混合物的前体和产物的方法。
