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[On the biotransformation of 2-methyl-3-o-toly-4(3H)-quinazolinone (=methaqualone. 1. Analysis and isolation of renal excretory products as well as the identification of some metabolites].

作者信息

Preuss F R, Hassler H M, Köpf R

出版信息

Arzneimittelforschung. 1966 Mar;16(3):395-401.

PMID:4964356
Abstract
摘要

相似文献

1
[On the biotransformation of 2-methyl-3-o-toly-4(3H)-quinazolinone (=methaqualone. 1. Analysis and isolation of renal excretory products as well as the identification of some metabolites].[关于2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮（=甲喹酮）的生物转化。1. 肾脏排泄产物的分析、分离及某些代谢物的鉴定]
Arzneimittelforschung. 1966 Mar;16(3):395-401.
2
[On the biotransformation of 2-methyl-3-o-tolyl-4(3H)-quinazolinone (Methaqualone). 2. On the structure and synthesis of some renal excretory products].
Arzneimittelforschung. 1966 Mar;16(3):401-7.
3
[Biotransformation of 2-methyl-3-o-tolyl-4(3H)-quinazolinone (Methaqualone). 3. Identification of 6-hydroxy-2-methyl-3-(3'-hydroxy-2'-methyl-phenyl)-4(3H)-quinazolinone as a renal elimination product of Methaqualone].
Arzneimittelforschung. 1970 Dec;20(12):1920-2.
4
Metabolism of methaqualone by the epoxide-diol pathway in man and the rat.
Drug Metab Dispos. 1975 Jul-Aug;3(4):287-96.
5
Metabolic fate of 2-methyl-3-o-tolyl-4(3H)-quinazolinone. 3. Metabolism of 2-methyl-3-o-tolyl-4(3H)-quinazolinone-N-oxide in vivo and in vitro.2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮的代谢命运。3. 2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮-N-氧化物的体内和体外代谢
Chem Pharm Bull (Tokyo). 1970 Jan;18(1):143-6. doi: 10.1248/cpb.18.143.
6
Urinary excretion of c-hydroxy derivatives of methaqualone in man.人尿液中安眠酮c-羟基衍生物的排泄情况。
Xenobiotica. 1976 Feb;6(2):125-34. doi: 10.3109/00498257609151621.
7
Metabolic fate of 2-methyl-3-o-tolyl-4(3H)-quinazolinone. II. Metabolism of 2-methyl-3-o-tolyl-4(3H)-quinazolinone by rabbits liver.2-甲基-3-邻甲苯基-4（3H）-喹唑啉酮的代谢命运。II. 兔肝脏对2-甲基-3-邻甲苯基-4（3H）-喹唑啉酮的代谢
Chem Pharm Bull (Tokyo). 1970 Jan;18(1):138-42. doi: 10.1248/cpb.18.138.
8
The isolation and identification of precursors and reaction products in the clandestine manufacture of methaqualone and mecloqualone.甲喹酮和甲氯喹酮非法制造过程中前体及反应产物的分离与鉴定
J Forensic Sci. 1985 Oct;30(4):1022-47.
9
[Analysis and biochemistry of aza analogues of methaqualone. Part 7: biotransformation of 2-methyl-3-(2'-methylphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidine (Kr 100) (author's transl)].甲喹酮氮杂类似物的分析与生物化学。第7部分：2-甲基-3-(2'-甲基苯基)-4-氧代-3,4-二氢吡啶并[2,3-d]嘧啶（Kr 100）的生物转化（作者译）
Pharmazie. 1979 Nov;34(11):732-5.
10
Biotransformation and excretion of nitromethaqualone in rats and humans.硝甲喹酮在大鼠和人体内的生物转化与排泄
J Pharm Sci. 1982 Oct;71(10):1152-7. doi: 10.1002/jps.2600711019.

引用本文的文献

1
Analysis of methaqualone in autopsy material.尸检材料中安眠酮的分析。
Z Rechtsmed. 1970;67(6):342-58. doi: 10.1007/BF02083041.
2
Detection of methaqualone and its metabolites in urine.尿液中安眠酮及其代谢物的检测。
J Clin Pathol. 1969 Sep;22(5):602-4. doi: 10.1136/jcp.22.5.602.
3
Long-term urinary excretion of methaqualone in a human subject.一名人类受试者中长期甲喹酮的尿液排泄情况。
J Pharmacokinet Biopharm. 1978 Apr;6(2):111-22. doi: 10.1007/BF01117446.
4
Serum concentrations of methaqualone after repeated oral doses of a combination formulation to human subjects.在人类受试者重复口服一种复方制剂后，甲喹酮的血清浓度。
Eur J Clin Pharmacol. 1976 Sep 30;10(5):343-7. doi: 10.1007/BF00565624.