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复发性特发性肉芽肿性乳腺炎:一例报告。

Recurrent Idiopathic Granulomatous Mastitis: A Case Report.

机构信息

Department of General Surgery, Mahakali Provincial Hospital, Mahendranagar, Kanchanpur, Nepal.

Lele Primary Health Care Centre, Lele, Lalitpur, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2024 Feb 24;62(270):136-138. doi: 10.31729/jnma.8442.

DOI:10.31729/jnma.8442
PMID:38409976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10924527/
Abstract

UNLABELLED

Idiopathic granulomatous mastitis is a rare benign breast disease of unknown aetiology mostly presenting as a breast abscess but not responding to usual conservative management with incision and drainage and frequently mimics breast cancer. We present a case 31-year-old female presented with complaints of right breast pain and redness who was initially diagnosed and treated as a case of breast abscess with repeated incision and drainage and antibiotics but did not improve. Later histopathology revealed granuloma with giant cell reaction and the patient was given a trial of steroids which showed no improvement. Wide local excision with a long course of broad-spectrum antibiotics was performed which led into remission. This case report highlights the importance of considering idiopathic granulomatous mastitis as differentials in non-responding breast abscesses. Histopathology for diagnosis and trial of wide local excision with a long course of broad-spectrum antibiotics as treatment may be done for management.

KEYWORDS

antibiotics; case reports; granuloma; mastitis.

摘要

中文译文:特发性肉芽肿性乳腺炎是一种罕见的良性乳腺疾病,病因不明,主要表现为乳腺脓肿,但常规的切开引流等保守治疗方法无效,且常与乳腺癌相混淆。我们报告 1 例 31 岁女性,因右乳房疼痛和发红就诊,最初被诊断为并接受了切开引流和抗生素治疗,但未见改善。后来的组织病理学显示为伴有巨细胞反应的肉芽肿,给予皮质类固醇治疗试验也未见改善。随后进行了广泛局部切除和长期广谱抗生素治疗,症状缓解。本病例报告强调了在非反应性乳腺脓肿中考虑特发性肉芽肿性乳腺炎作为鉴别诊断的重要性。组织病理学诊断和广泛局部切除联合长期广谱抗生素治疗试验可能有助于疾病的管理。

关键词:抗生素;病例报告;肉芽肿;乳腺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e522/10924527/5e9f38a67cd2/JNMA-62-270-136-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e522/10924527/c62d84f98593/JNMA-62-270-136-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e522/10924527/5e9f38a67cd2/JNMA-62-270-136-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e522/10924527/c62d84f98593/JNMA-62-270-136-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e522/10924527/5e9f38a67cd2/JNMA-62-270-136-g2.jpg

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本文引用的文献

1
Idiopathic Granulomatous Mastitis: A Rare Confrontation.特发性肉芽肿性乳腺炎:一种罕见的疾病
Cureus. 2021 Nov 9;13(11):e19420. doi: 10.7759/cureus.19420. eCollection 2021 Nov.
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Idiopathic granulomatous mastitis: challenges of treatment in iranian women.特发性肉芽肿性乳腺炎:伊朗女性治疗面临的挑战。
BMC Surg. 2021 Apr 21;21(1):206. doi: 10.1186/s12893-021-01210-6.
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Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature.特发性肉芽肿性乳腺炎——一个有待解开的谜团:病例系列及文献综述
Cureus. 2020 Feb 5;12(2):e6895. doi: 10.7759/cureus.6895.
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Idiopathic granulomatous mastitis: dilemmas in diagnosis and treatment.特发性肉芽肿性乳腺炎:诊断与治疗中的困境
Electron Physician. 2017 Sep 25;9(9):5375-5379. doi: 10.19082/5375. eCollection 2017 Sep.
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Idiopathic granulomatous mastitis: an institutional experience.特发性肉芽肿性乳腺炎:一项机构经验
Turk J Surg. 2017 Jun 1;33(2):100-103. doi: 10.5152/turkjsurg.2017.3439. eCollection 2017.
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Idiopathic Granulomatous Mastitis: Comparison of Wide Local Excision with or without Corticosteroid Therapy.特发性肉芽肿性乳腺炎:广泛切除术联合或不联合皮质类固醇治疗的比较。
Breast Care (Basel). 2014 May;9(2):111-5. doi: 10.1159/000360926.
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Idiopathic granulomatous mastitis in Hispanic women - Indiana, 2006-2008.2006 - 2008年印第安纳州西班牙裔女性特发性肉芽肿性乳腺炎
MMWR Morb Mortal Wkly Rep. 2009 Dec 4;58(47):1317-21.
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The role of conservative treatment in idiopathic granulomatous mastitis.保守治疗在特发性肉芽肿性乳腺炎中的作用。
Breast J. 2005 Nov-Dec;11(6):454-6. doi: 10.1111/j.1075-122X.2005.00127.x.
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Idiopathic granulomatous mastitis: time to avoid unnecessary mastectomies.特发性肉芽肿性乳腺炎:是时候避免不必要的乳房切除术了。
Breast J. 2004 Jul-Aug;10(4):318-22. doi: 10.1111/j.1075-122X.2004.21336.x.