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新生儿入住三级护理中心新生儿重症监护病房后的败血症。

Sepsis among Neonates Admitted to a Neonatal Intensive Care Unit in a Tertiary Care Centre.

机构信息

Nepalgunj Medical College and Teaching Hospital, Nepalgunj, Banke, Nepal.

Department of Pediatrics, Nepalgunj Medical College and Teaching Hospital, Nepalgunj, Banke, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2024 Feb 24;62(270):76-78. doi: 10.31729/jnma.8431.

DOI:10.31729/jnma.8431
PMID:38409987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10924525/
Abstract

INTRODUCTION

Neonatal sepsis is a condition that carries a high risk for mortality as neonates rapidly transition to extra-uterine life and are subjected to various risk factors. Sepsis prevalence can be reduced by good antenatal care, early detection and treatment of risk factors. The study aimed to find out the prevalence of sepsis among neonates admitted to a neonatal intensive care unit in a tertiary care centre.

METHODS

This is a descriptive cross-sectional study conducted among neonates admitted to the neonatal care unit of a tertiary care centre after obtaining ethical approval from the Institutional Review Committee. Data of patients admitted from 12 December 2022 to 30 June 2023 was collected from hospital records. Symptomatic patients admitted to the neonatal intensive care unit were included and those with incomplete data were excluded from the study. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.

RESULTS

Among 379 neonates, the prevalence of sepsis was 138 (36.41%) (28.38-44.44, 95% Confidence Interval). A total of 98 (71.01%) had early-onset neonatal sepsis and 40 (28.99%) had late-onset neonatal sepsis.

CONCLUSIONS

The prevalence of neonatal sepsis was found to be lower than other studies done in similar settings.

KEYWORDS

neonate; neonatal sepsis; prematurity; prevalence.

摘要

简介

新生儿败血症是一种死亡率很高的疾病,因为新生儿迅速过渡到宫外生活,并面临各种风险因素。通过良好的产前保健、早期发现和治疗风险因素,可以降低败血症的患病率。本研究旨在了解三级保健中心新生儿重症监护病房新生儿败血症的患病率。

方法

这是一项在获得机构审查委员会的伦理批准后,在三级保健中心的新生儿护理病房进行的描述性横断面研究。从 2022 年 12 月 12 日至 2023 年 6 月 30 日期间,从医院记录中收集了入住新生儿重症监护病房的患者的数据。纳入有症状的入住新生儿重症监护病房的患者,并排除数据不完整的患者。采用便利抽样法。点估计值在 95%置信区间计算。

结果

在 379 名新生儿中,败血症的患病率为 138 例(36.41%)(28.38-44.44,95%置信区间)。共有 98 例(71.01%)为早发型新生儿败血症,40 例(28.99%)为晚发型新生儿败血症。

结论

新生儿败血症的患病率低于在类似环境中进行的其他研究。

关键词

新生儿;新生儿败血症;早产;患病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/214b/10924525/7cfcf6eecc7e/JNMA-62-270-76-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/214b/10924525/7cfcf6eecc7e/JNMA-62-270-76-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/214b/10924525/7cfcf6eecc7e/JNMA-62-270-76-g1.jpg

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BMC Pediatr. 2022 Dec 15;22(1):716. doi: 10.1186/s12887-022-03779-0.
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Indications and Clinical Profile of Neonatal Admissions: A Cross-Sectional Descriptive Analysis from a Single Academic Center in Jordan.新生儿入院的适应症及临床概况:来自约旦一个学术中心的横断面描述性分析
J Multidiscip Healthc. 2020 Sep 23;13:997-1006. doi: 10.2147/JMDH.S275267. eCollection 2020.
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Bacteriological profile of neonatal sepsis and antibiotic susceptibility pattern of isolates admitted at Kanti Children's Hospital, Kathmandu, Nepal.
尼泊尔加德满都坎蒂儿童医院收治的新生儿败血症细菌学特征及分离株的抗生素敏感性模式
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Semin Perinatol. 2003 Aug;27(4):293-301. doi: 10.1016/s0146-0005(03)00046-6.