产科和妇科病房收治的孕妇蛋白尿。

Proteinuria among Pregnant Women Admitted to the Department of Obstetrics and Gynaecology of a Tertiary Care Centre.

机构信息

Department of Obstetrics and Gynaecology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2024 Jan 2;62(269):9-12. doi: 10.31729/jnma.8388.

DOI:10.31729/jnma.8388

PMID:38410018

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10924488/

Abstract

INTRODUCTION

Proteinuria is usually related with preeclampsia during pregnancy, although it can also be caused by other conditions such as renal disease or isolated proteinuria. Proteinuria during pregnancy can result in adverse fetomaternal outcomes. The study aimed to find the prevalence of proteinuria among pregnant women admitted to the Department of Obstetrics and Gynaecology of a tertiary care centre.

METHODS

A descriptive cross-sectional study was carried out among pregnant women in the Department of Obstetrics and Gynaecology after obtaining ethical approval from the Institutional Review Committee. Data of 14 April 2022 to 13 April 2023 was collected from 9 June 2023 to 9 September 2023 from medical records. The study included pregnant women aged 18-45 years, who were past 28 weeks of gestation and had a 24-hour urine protein measurement. Pregnant women who had insufficient medical records were excluded from the study. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.

RESULTS

Among 3,914 pregnant women, proteinuria was seen in 61 (1.56%) (1.17-1.95, 95% Confidence Interval). The mean proteinuria in the study group was 1.5±2.75 gm/24 hr. In pregnant women with proteinuria, maternal complications were seen in 51 (83.60%) and foetal complications in 34 (55.73%) cases. A total of 47 (77.05%) underwent emergency lower-section caesarean section.

CONCLUSIONS

The prevalence of proteinuria among pregnant women was found to be similar as compared to studies done in similar settings.

KEYWORDS

preeclampsia; pregnancy complications; proteinuria.

摘要

简介

蛋白尿通常与怀孕期间的子痫前期有关，尽管它也可能由其他疾病引起，如肾脏疾病或孤立性蛋白尿。怀孕期间的蛋白尿可能导致母婴不良结局。本研究旨在调查在一家三级保健中心妇产科就诊的孕妇中蛋白尿的患病率。

方法

在获得机构审查委员会的伦理批准后，在妇产科对孕妇进行了描述性横断面研究。从 2023 年 6 月 9 日至 9 月 9 日，从病历中收集了 2022 年 4 月 14 日至 2023 年 4 月 13 日期间的孕妇数据。本研究纳入了年龄在 18-45 岁之间、妊娠 28 周以上且进行 24 小时尿液蛋白测量的孕妇。研究排除了病历不完整的孕妇。采用便利抽样法。计算了 95%置信区间的点估计值。

结果

在 3914 名孕妇中，有 61 名（1.56%）（1.17-1.95，95%置信区间）出现蛋白尿。研究组的平均蛋白尿为 1.5±2.75 gm/24 小时。在有蛋白尿的孕妇中，51 例（83.60%）出现母体并发症，34 例（55.73%）出现胎儿并发症。共有 47 例（77.05%）接受紧急下段剖宫产。