Woehrle Holger, Schoebel Christoph, Ficker Joachim H, Graml Andrea, Schnepf Jürgen, Fietze Ingo, Young Peter, Arzt Michael
Sleep and Ventilation Center Blaubeuren, Lung Center Ulm, Ulm, Germany.
Department of Sleep Medicine, University Duisburg-Essen, Essen, Germany.
ERJ Open Res. 2024 Feb 26;10(1). doi: 10.1183/23120541.00424-2023. eCollection 2024 Jan.
Telemonitoring-guided interventions can improve short-term positive airway pressure (PAP) therapy adherence, but long-term effects are unknown. This study investigated long-term PAP therapy termination in patients with sleep apnoea managed with standard care, telemonitoring-guided proactive care or telemonitoring-guided proactive care + patient engagement tool.
German healthcare provider data were analysed retrospectively. Individuals aged 18-100 years who started PAP from 2014 to 2019 and had device type/interface data were included. Time-to-termination periods were analysed using Kaplan-Meier plots and Cox proportional hazards regression, adjusted for age, sex, insurance type, and device and mask type.
The per-protocol population (valid telemonitoring data) included 104 612 individuals (71% male; 95% aged >40 years). Mean follow-up was 3.3±2.0 years. The overall therapy termination rate was significantly lower in the telemonitoring-guided proactive care group standard care (20% 27%; p<0.001), and even lower in the telemonitoring-guided care + patient engagement tool group (11%; p<0.001 other treatment groups). Adjusted risk of therapy termination was lower standard care (hazard ratio 0.76, 95% confidence interval 0.74-0.78; and 0.41 (0.38-0.44) for telemonitoring-guided proactive care alone + patient engagement). Age <50 or >59 years and use of a nasal pillows or full-face mask were significant predictors of therapy termination; male sex, use of telemonitoring-guided proactive care (± patient engagement) and private insurance were significantly associated with lower therapy termination rates.
Use of telemonitoring-guided proactive care and a patient engagement tool was associated with lower rates of PAP therapy termination.
远程监测引导的干预措施可提高短期持续气道正压通气(PAP)治疗的依从性,但长期效果尚不清楚。本研究调查了采用标准护理、远程监测引导的主动护理或远程监测引导的主动护理+患者参与工具管理的睡眠呼吸暂停患者长期PAP治疗终止情况。
对德国医疗服务提供商的数据进行回顾性分析。纳入2014年至2019年开始使用PAP且有设备类型/接口数据的18至100岁个体。使用Kaplan-Meier曲线和Cox比例风险回归分析终止治疗时间,对年龄、性别、保险类型以及设备和面罩类型进行校正。
符合方案人群(有效远程监测数据)包括104612名个体(71%为男性;95%年龄>40岁)。平均随访时间为3.3±2.0年。远程监测引导的主动护理组的总体治疗终止率显著低于标准护理组(20%对27%;p<0.001),在远程监测引导护理+患者参与工具组中甚至更低(11%;p<0.001对其他治疗组)。校正后的治疗终止风险低于标准护理组(风险比0.76,95%置信区间0.74-0.78;单独的远程监测引导主动护理+患者参与为0.41(0.38-0.44))。年龄<50岁或>59岁以及使用鼻枕或全面罩是治疗终止的显著预测因素;男性、使用远程监测引导的主动护理(±患者参与)和私人保险与较低的治疗终止率显著相关。
使用远程监测引导的主动护理和患者参与工具与较低的PAP治疗终止率相关。